Expression of ABHD13 in cancer - Summary - The Human Protein Atlas

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ABHD13

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ABHD13
Gene description	Abhydrolase domain containing 13
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in several tissue types

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification. Presumed off target binding observed and disregarded.
Reliability score	Approved based on 2 antibodies. HPA032143 , HPA032144
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA032143	HPA032144

GENE INFORMATION
Gene name	ABHD13 (HGNC Symbol)
Synonyms	bA153I24.2, BEM46L1, C13orf6, FLJ14906
Description	Abhydrolase domain containing 13 (HGNC Symbol)
Entrez gene summary
Chromosome	13
Cytoband	q33.3
Chromosome location (bp)	108218379 - 108234255
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000139826 (version 83.38)
Entrez gene	84945
UniProt	Q7L211 (UniProt - Evidence at transcript level)
neXtProt	NX_Q7L211
Antibodypedia	ABHD13 antibodies

PROTEIN BROWSER

ABHD13-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ABHD13-001 ENSP00000365063 ENST00000375898	Q7L211 [Direct mapping] Alpha/beta hydrolase domain-containing protein 13 A0A024RDX1 [Target identity:100%; Query identity:100%] Abhydrolase domain containing 13, isoform CRA_a Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0008152 [metabolic process] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0016787 [hydrolase activity] Show all	337 aa 38.5 kDa	No	1

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.