Fields »
ABOUT
HELP
BLOG
JDP2

GENERAL INFORMATION

Gene name

 JDP2

Gene description

 Jun dimerization protein 2

Protein class

 Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 5
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Mixed
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 General nuclear expression.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Supported based on 1 antibody.
HPA059511
SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in colorectal cancer (unfavourable).
Colorectal cancer p<0.001
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer

STAINING SUMMARY
HPA059511

GENE INFORMATION

Gene name

 JDP2 (HGNC Symbol)

Synonyms

 JUNDM2

Description

 Jun dimerization protein 2 (HGNC Symbol)

Entrez gene summary

Chromosome

 14

Cytoband

 q24.3

Chromosome location (bp)

 75427716 - 75474111

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000140044 (version 83.38)

Entrez gene

 122953

UniProt

 Q8WYK2 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8WYK2

Antibodypedia

 JDP2 antibodies

PROTEIN BROWSER
JDP2-001
JDP2-002
JDP2-003
JDP2-004
JDP2-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
JDP2-001
ENSP00000399587
ENST00000435893
Q8WYK2 [Direct mapping]
Jun dimerization protein 2
A0A024R6D7 [Target identity:100%; Query identity:100%]
Jun dimerization protein 2, isoform CRA_a
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding]
GO:0000982 [transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0043565 [sequence-specific DNA binding]
Show all
 163 aa
18.7 kDa 		No 0
JDP2-002
ENSP00000452769
ENST00000559060
H0YKE4 [Direct mapping]
Jun dimerization protein 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005654 [nucleoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0031063 [regulation of histone deacetylation]
GO:0043565 [sequence-specific DNA binding]
Show all
 134 aa
15.4 kDa 		No 0
JDP2-003
ENSP00000267569
ENST00000267569
Q8WYK2 [Direct mapping]
Jun dimerization protein 2
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding]
GO:0000982 [transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0001078 [transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0003677 [DNA binding]
GO:0003682 [chromatin binding]
GO:0003690 [double-stranded DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0031065 [positive regulation of histone deacetylation]
GO:0043565 [sequence-specific DNA binding]
GO:0045599 [negative regulation of fat cell differentiation]
GO:0046982 [protein heterodimerization activity]
Show all
 174 aa
19.8 kDa 		No 0
JDP2-004
ENSP00000415558
ENST00000419727
Q8WYK2 [Direct mapping]
Jun dimerization protein 2
A0A024R6D7 [Target identity:100%; Query identity:100%]
Jun dimerization protein 2, isoform CRA_a
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding]
GO:0000982 [transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0043565 [sequence-specific DNA binding]
Show all
 163 aa
18.7 kDa 		No 0
JDP2-201
ENSP00000409787
ENST00000437176
Q8WYK2 [Direct mapping]
Jun dimerization protein 2
A0A024R6D7 [Target identity:100%; Query identity:100%]
Jun dimerization protein 2, isoform CRA_a
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding]
GO:0000982 [transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0043565 [sequence-specific DNA binding]
Show all
 163 aa
18.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.