Cell atlas - ANP32A - The Human Protein Atlas

GENERAL INFORMATION
Gene name	ANP32A
Gene description	Acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleoplasm. In addition localized to the cytosol & centrosome. Caution: Based on antibodies targeting proteins from multiple genes.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (supported)
Additional location	In addition localized to the Centrosome (uncertain), Cytosol (approved)

DATA RELIABILITY
Reliability score	Approved based on 2 antibodies. HPA063133 , HPA067561
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ASSAYS

RNA expression

Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleoplasm. In addition localized to the cytosol & centrosome. Caution: Based on antibodies targeting proteins from multiple genes.

Main location

Nucleoplasm (supported)

Additional location

Centrosome (uncertain), Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location
HPA063133	MCF7	Nucleoplasm
HPA063133	MCF7	Cytosol
HPA063133	RH-30	Nucleoplasm
		Centrosome
		Cytosol
HPA063133	U-2 OS	Nucleoplasm
HPA063133	U-2 OS	Centrosome
HPA067561	HEK 293	Nucleoplasm
HPA067561	SK-MEL-30	Nucleoplasm
HPA067561	SK-MEL-30	Centrosome
HPA067561	U-2 OS	Nucleoplasm

GENE INFORMATION
Gene name	ANP32A (HGNC Symbol)
Synonyms	C15orf1, I1PP2A, LANP, MAPM, mapmodulin, PHAPI, PP32
Description	Acidic (leucine-rich) nuclear phosphoprotein 32 family, member A (HGNC Symbol)
Entrez gene summary
Chromosome	15
Cytoband	q23
Chromosome location (bp)	68778535 - 68820897
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000140350 (version 83.38)
Entrez gene	8125
UniProt	P39687 (UniProt - Evidence at protein level)
neXtProt	NX_P39687
Antibodypedia	ANP32A antibodies

PROTEIN BROWSER

ANP32A-001	ANP32A-010

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ANP32A-001 ENSP00000417864 ENST00000465139	P39687 [Direct mapping] Acidic leucine-rich nuclear phosphoprotein 32 family member A Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0006913 [nucleocytoplasmic transport] GO:0010467 [gene expression] GO:0035556 [intracellular signal transduction] GO:0043488 [regulation of mRNA stability] GO:0044822 [poly(A) RNA binding] GO:0048471 [perinuclear region of cytoplasm] Show all	249 aa 28.6 kDa	No	0
ANP32A-010 ENSP00000453838 ENST00000560303	H0YN26 [Direct mapping] Acidic leucine-rich nuclear phosphoprotein 32 family member A Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	177 aa 20 kDa	No	0