Fields »
ABOUT
HELP
BLOG
RLBP1

GENERAL INFORMATION

Gene name

 RLBP1

Gene description

 Retinaldehyde binding protein 1

Protein class

 Disease related genes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Group enriched (glioma, melanoma)
HPA (cell line):Cell line enriched (SK-MEL-30)
HPA (normal tissue):Tissue enriched (cerebral cortex)

Protein evidence

 Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Group enriched (glioma, melanoma)

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 RLBP1 (HGNC Symbol)

Synonyms

 CRALBP

Description

 Retinaldehyde binding protein 1 (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene is a 36-kD water-soluble protein which carries 11-cis-retinaldehyde or 11-cis-retinal as physiologic ligands. It may be a functional component of the visual cycle. Mutations of this gene have been associated with severe rod-cone dystrophy, Bothnia dystrophy (nonsyndromic autosomal recessive retinitis pigmentosa) and retinitis punctata albescens. [provided by RefSeq, Jul 2008]

Chromosome

 15

Cytoband

 q26.1

Chromosome location (bp)

 89209869 - 89221751

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000140522 (version 83.38)

Entrez gene

 6017

UniProt

 P12271 (UniProt - Evidence at protein level)

neXtProt

 NX_P12271

Antibodypedia

 RLBP1 antibodies

PROTEIN BROWSER
RLBP1-001
RLBP1-005

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RLBP1-001
ENSP00000268125
ENST00000268125
P12271 [Direct mapping]
Retinaldehyde-binding protein 1
Show all
   MEMSAT-SVM predicted membrane proteins
Predicted intracellular proteins
Disease related genes
Protein evidence (Kim et al 2014)
Show all
GO:0001523 [retinoid metabolic process]
GO:0005215 [transporter activity]
GO:0005502 [11-cis retinal binding]
GO:0005575 [cellular_component]
GO:0005829 [cytosol]
GO:0006776 [vitamin A metabolic process]
GO:0006810 [transport]
GO:0007601 [visual perception]
GO:0007603 [phototransduction, visible light]
GO:0019841 [retinol binding]
GO:0044297 [cell body]
Show all
 317 aa
36.5 kDa 		No 0
RLBP1-005
ENSP00000454740
ENST00000563254
H3BN92 [Direct mapping]
Retinaldehyde-binding protein 1
Show all
Predicted intracellular proteins
Show all
GO:0005215 [transporter activity]
GO:0005622 [intracellular]
GO:0006810 [transport]
Show all
 108 aa
12.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.