Tissue expression of ARHGAP17 - Summary - The Human Protein Atlas

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ARHGAP17

TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	ARHGAP17
Gene description	Rho GTPase activating protein 17
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic and nuclear expression in several tissues.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Approved based on 1 antibody. HPA041703
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	ARHGAP17 (HGNC Symbol)
Synonyms	FLJ10308, FLJ13219, NADRIN, RICH1, WBP15
Description	Rho GTPase activating protein 17 (HGNC Symbol)
Entrez gene summary	RICH1 is a GTPase-activating protein (GAP). GAPs stimulate the intrinsic GTP hydrolysis of small G proteins, such as RHOA (MIM 165390), RAC1 (MIM 602048), and CDC42 (MIM 116952).[supplied by OMIM, Apr 2004]
Chromosome	16
Cytoband	p12.1
Chromosome location (bp)	24919385 - 25015666
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000140750 (version 83.38)
Entrez gene	55114
UniProt	Q68EM7 (UniProt - Evidence at protein level)
neXtProt	NX_Q68EM7
Antibodypedia	ARHGAP17 antibodies

PROTEIN BROWSER

ARHGAP17-001	ARHGAP17-002	ARHGAP17-006	ARHGAP17-007	ARHGAP17-013	ARHGAP17-014	ARHGAP17-023

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ARHGAP17-001 ENSP00000289968 ENST00000289968	Q68EM7 [Direct mapping] Rho GTPase-activating protein 17 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005096 [GTPase activator activity] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0005923 [bicellular tight junction] GO:0007165 [signal transduction] GO:0007264 [small GTPase mediated signal transduction] GO:0017124 [SH3 domain binding] GO:0043547 [positive regulation of GTPase activity] GO:0051056 [regulation of small GTPase mediated signal transduction] Show all	881 aa 95.4 kDa	No	0
ARHGAP17-002 ENSP00000303130 ENST00000303665	Q68EM7 [Direct mapping] Rho GTPase-activating protein 17 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005096 [GTPase activator activity] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0005923 [bicellular tight junction] GO:0007165 [signal transduction] GO:0007264 [small GTPase mediated signal transduction] GO:0017124 [SH3 domain binding] GO:0043547 [positive regulation of GTPase activity] GO:0051056 [regulation of small GTPase mediated signal transduction] Show all	803 aa 87.6 kDa	No	0
ARHGAP17-006 ENSP00000460600 ENST00000571406	I3L3P1 [Direct mapping] Rho GTPase-activating protein 17 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		95 aa 9.4 kDa	No	0
ARHGAP17-007 ENSP00000461639 ENST00000571843	I3L4Y5 [Direct mapping] Rho GTPase-activating protein 17 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		128 aa 13 kDa	No	0
ARHGAP17-013 ENSP00000461426 ENST00000573449	I3L4P6 [Direct mapping] Rho GTPase-activating protein 17 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] Show all	76 aa 8.6 kDa	No	0
ARHGAP17-014 ENSP00000406701 ENST00000455311	C9IZD3 [Direct mapping] Rho GTPase-activating protein 17 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] Show all	211 aa 24 kDa	No	0
ARHGAP17-023 ENSP00000460985 ENST00000573765	I3L460 [Direct mapping] Rho GTPase-activating protein 17 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		235 aa 24 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.