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RPL3L

GENERAL INFORMATION

Gene name

 RPL3L

Gene description

 Ribosomal protein L3-like

Protein class

 Predicted intracellular proteins
Ribosomal proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (skeletal muscle)
GTEx:Group enriched (heart muscle, skeletal muscle)
FANTOM5:Group enriched (heart muscle, skeletal muscle)

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in skeletal and heart muscle.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Presumed off target binding observed and disregarded.

Reliability score

 Supported based on 1 antibody.
HPA049136
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Heart muscle

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (skeletal muscle)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (heart muscle, skeletal muscle)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (heart muscle, skeletal muscle)

GENE INFORMATION

Gene name

 RPL3L

Synonyms

Description

 Ribosomal protein L3-like (HGNC Symbol)

Entrez gene summary

 This gene encodes a protein that shares sequence similarity with ribosomal protein L3. The protein belongs to the L3P family of ribosomal proteins. Unlike the ubiquitous expression of ribosomal protein genes, this gene has a tissue-specific pattern of expression, with the highest levels of expression in skeletal muscle and heart. It is not currently known whether the encoded protein is a functional ribosomal protein or whether it has evolved a function that is independent of the ribosome. [provided by RefSeq, Jul 2008]

Chromosome

 16

Cytoband

 p13.3

Chromosome location (bp)

 1943974 - 1957606

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000140986 (version 83.38)

Entrez gene

 6123

UniProt

 Q92901 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q92901

Antibodypedia

 RPL3L antibodies

PROTEIN BROWSER
RPL3L-001
RPL3L-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RPL3L-001
ENSP00000268661
ENST00000268661
Q92901 [Direct mapping]
60S ribosomal protein L3-like
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Ribosomal proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000027 [ribosomal large subunit assembly]
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0003723 [RNA binding]
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005829 [cytosol]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006414 [translational elongation]
GO:0006415 [translational termination]
GO:0006614 [SRP-dependent cotranslational protein targeting to membrane]
GO:0010467 [gene expression]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0022625 [cytosolic large ribosomal subunit]
GO:0044267 [cellular protein metabolic process]
GO:0044822 [poly(A) RNA binding]
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 407 aa
46.3 kDa 		No 0
RPL3L-003
ENSP00000455856
ENST00000565426
H3BQN3 [Direct mapping]
60S ribosomal protein L3-like
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005840 [ribosome]
GO:0006412 [translation]
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 43 aa
4.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.