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Cancers generally showed moderate nuclear positivity.
GENE INFORMATION
Gene name
MYOCD (HGNC Symbol)
Synonyms
MYCD
Description
Myocardin (HGNC Symbol)
Entrez gene summary
This gene encodes a nuclear protein, which is expressed in heart, aorta, and in smooth muscle cell-containing tissues. It functions as a transcriptional co-activator of serum response factor (SRF) and modulates expression of cardiac and smooth muscle-specific SRF-target genes, and thus may play a crucial role in cardiogenesis and differentiation of the smooth muscle cell lineage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]