Expression of GREB1L in cancer - Summary - The Human Protein Atlas

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GREB1L

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	GREB1L
Gene description	Growth regulation by estrogen in breast cancer-like
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enhanced (AF22, BEWO, CACO-2)
HPA (normal tissue):	Tissue enhanced (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 2 antibodies. HPA041647 , HPA044218
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA041647	HPA044218

GENE INFORMATION
Gene name	GREB1L (HGNC Symbol)
Synonyms	C18orf6, FLJ13687, KIAA1772
Description	Growth regulation by estrogen in breast cancer-like (HGNC Symbol)
Entrez gene summary
Chromosome	18
Cytoband
Chromosome location (bp)	21242242 - 21525417
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000141449 (version 83.38)
Entrez gene	80000
UniProt	Q9C091 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9C091
Antibodypedia	GREB1L antibodies

PROTEIN BROWSER

GREB1L-003	GREB1L-005	GREB1L-006	GREB1L-009	GREB1L-010	GREB1L-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GREB1L-003 ENSP00000464162 ENST00000580732	Q9C091 [Direct mapping] GREB1-like protein Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	1923 aa 214.4 kDa	No	0
GREB1L-005 ENSP00000463926 ENST00000579454	J3QQW0 [Direct mapping] GREB1-like protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		200 aa 21 kDa	No	0
GREB1L-006 ENSP00000463976 ENST00000581327	J3QR03 [Direct mapping] GREB1-like protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		175 aa 19.6 kDa	No	0
GREB1L-009 ENSP00000462152 ENST00000580384	J3KRT4 [Direct mapping] GREB1-like protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		190 aa 21.5 kDa	No	0
GREB1L-010 ENSP00000269218 ENST00000269218	Q9C091 [Direct mapping] GREB1-like protein Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	1814 aa 202.1 kDa	No	0
GREB1L-201 ENSP00000412060 ENST00000424526	Q9C091 [Direct mapping] GREB1-like protein Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	1923 aa 214.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.