Expression of CBLN2 in cancer - Summary - The Human Protein Atlas

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CBLN2

TISSUE

CELL

PATHOLOGY

GENERAL INFORMATION
Gene name	CBLN2
Gene description	Cerebellin 2 precursor
Protein class	Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enriched (breast cancer)
HPA (cell line):	Cell line enriched (SH-SY5Y)
HPA (normal tissue):	Group enriched (cerebral cortex, seminal vesicle)

Protein evidence

Evidence at protein level

ANTIBODY IHC RELIABILITY
Reliability score	Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enriched (breast cancer)

PROTEIN EXPRESSION
Pending cancer tissue analysis
STAINING SUMMARY

GENE INFORMATION
Gene name	CBLN2
Synonyms
Description	Cerebellin 2 precursor (HGNC Symbol)
Entrez gene summary
Chromosome	18
Cytoband	q22.3
Chromosome location (bp)	72536680 - 72638521
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000141668 (version 83.38)
Entrez gene	147381
UniProt	Q8IUK8 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8IUK8
Antibodypedia	CBLN2 antibodies

PROTEIN BROWSER

CBLN2-001	CBLN2-002	CBLN2-004	CBLN2-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CBLN2-001 ENSP00000269503 ENST00000269503	Q8IUK8 [Direct mapping] Cerebellin-2 A0A024R380 [Target identity:100%; Query identity:100%] Cerebellin 2, isoform CRA_a Show all	MEMSAT3 predicted membrane proteins THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0005615 [extracellular space] GO:0051965 [positive regulation of synapse assembly] Show all	224 aa 24.1 kDa	Yes	0
CBLN2-002 ENSP00000463771 ENST00000585159	Q8IUK8 [Direct mapping] Cerebellin-2 A0A024R380 [Target identity:100%; Query identity:100%] Cerebellin 2, isoform CRA_a Show all	MEMSAT3 predicted membrane proteins THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005515 [protein binding] Show all	224 aa 24.1 kDa	Yes	0
CBLN2-004 ENSP00000464490 ENST00000584764	J3QS23 [Direct mapping] Cerebellin-2 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	108 aa 12.2 kDa	No	0
CBLN2-006 ENSP00000462632 ENST00000581073	J3KST0 [Direct mapping] Cerebellin-2 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	110 aa 12.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.