Expression of TMEM61 in cancer - Summary - The Human Protein Atlas

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TMEM61

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	TMEM61
Gene description	Transmembrane protein 61
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enriched (RPMI-8226)
HPA (normal tissue):	Tissue enhanced (parathyroid gland, salivary gland)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA030614
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable) and colorectal cancer (favourable).
Renal cancer p<0.001 Colorectal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA030614

GENE INFORMATION
Gene name	TMEM61
Synonyms
Description	Transmembrane protein 61 (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	p32.3
Chromosome location (bp)	54980792 - 54992293
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000143001 (version 83.38)
Entrez gene	199964
UniProt	Q8N0U2 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8N0U2
Antibodypedia	TMEM61 antibodies

PROTEIN BROWSER

TMEM61-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TMEM61-001 ENSP00000360315 ENST00000371268	Q8N0U2 [Direct mapping] Transmembrane protein 61 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	210 aa 22.2 kDa	No	1

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.