Expression of UFC1 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

UFC1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	UFC1
Gene description	Ubiquitin-fold modifier conjugating enzyme 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression at variable levels in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Approved based on 2 antibodies. HPA027481 , HPA028722
	SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable).
Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

Pancreatic cancer

STAINING SUMMARY

HPA027481	HPA028722

GENE INFORMATION
Gene name	UFC1 (HGNC Symbol)
Synonyms	HSPC155
Description	Ubiquitin-fold modifier conjugating enzyme 1 (HGNC Symbol)
Entrez gene summary	UFC1 is an E2-like conjugating enzyme for ubiquitin-fold modifier-1 (UFM1; MIM 610553) (Komatsu et al., 2004 [PubMed 15071506]).[supplied by OMIM, Mar 2008]
Chromosome	1
Cytoband	q23.3
Chromosome location (bp)	161152776 - 161158856
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000143222 (version 83.38)
Entrez gene	51506
UniProt	Q9Y3C8 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y3C8
Antibodypedia	UFC1 antibodies

PROTEIN BROWSER

UFC1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
UFC1-001 ENSP00000356982 ENST00000368003	Q9Y3C8 [Direct mapping] Ubiquitin-fold modifier-conjugating enzyme 1 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0034976 [response to endoplasmic reticulum stress] GO:0070062 [extracellular exosome] GO:0071568 [UFM1 transferase activity] GO:0071569 [protein ufmylation] GO:1990592 [protein K69-linked ufmylation] Show all	167 aa 19.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.