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Malignancies were generally negative. Several cases of malignant gliomas, prostate, colorectal, cervical and testicular cancers displayed weak to moderate immunoreactivity in fractions of cells.
GENE INFORMATION
Gene name
LHX9
Synonyms
Description
LIM homeobox 9 (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the LIM homeobox gene family of developmentally expressed transcription factors. The encoded protein contains a homeodomain and two cysteine-rich zinc-binding LIM domains involved in protein-protein interactions. The protein is highly similar to a mouse protein that causes gonadal agenesis when inactivated, suggesting a role in gonadal development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]