Tissue expression of INTS7 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	INTS7
Gene description	Integrator complex subunit 7
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (testis)
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (testis)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	INTS7 (HGNC Symbol)
Synonyms	C1orf73, DKFZP434B168, INT7
Description	Integrator complex subunit 7 (HGNC Symbol)
Entrez gene summary	This gene encodes a subunit of the integrator complex. The integrator complex associates with the C-terminal domain of RNA polymerase II and mediates 3'-end processing of the small nuclear RNAs U1 and U2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
Chromosome	1
Cytoband	q32.3
Chromosome location (bp)	211940399 - 212035542
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000143493 (version 83.38)
Entrez gene	25896
UniProt	Q9NVH2 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NVH2
Antibodypedia	INTS7 antibodies

PROTEIN BROWSER

INTS7-001	INTS7-003	INTS7-004	INTS7-010	INTS7-012

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
INTS7-001 ENSP00000355961 ENST00000366994	Q9NVH2 [Direct mapping] Integrator complex subunit 7 Show all	MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000077 [DNA damage checkpoint] GO:0005488 [binding] GO:0005515 [protein binding] GO:0005694 [chromosome] GO:0016180 [snRNA processing] GO:0032039 [integrator complex] GO:0071479 [cellular response to ionizing radiation] Show all	962 aa 106.8 kDa	No	0
INTS7-003 ENSP00000355960 ENST00000366993	Q9NVH2 [Direct mapping] Integrator complex subunit 7 Show all	MEMSAT3 predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000077 [DNA damage checkpoint] GO:0005488 [binding] GO:0005515 [protein binding] GO:0005694 [chromosome] GO:0016180 [snRNA processing] GO:0032039 [integrator complex] GO:0071479 [cellular response to ionizing radiation] Show all	948 aa 105.2 kDa	No	0
INTS7-004 ENSP00000355959 ENST00000366992	Q9NVH2 [Direct mapping] Integrator complex subunit 7 Show all	MEMSAT3 predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000077 [DNA damage checkpoint] GO:0005488 [binding] GO:0005515 [protein binding] GO:0005694 [chromosome] GO:0016180 [snRNA processing] GO:0032039 [integrator complex] GO:0071479 [cellular response to ionizing radiation] Show all	942 aa 104.7 kDa	No	0
INTS7-010 ENSP00000388908 ENST00000440600	Q9NVH2 [Direct mapping] Integrator complex subunit 7 Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000077 [DNA damage checkpoint] GO:0005488 [binding] GO:0005515 [protein binding] GO:0005694 [chromosome] GO:0016180 [snRNA processing] GO:0032039 [integrator complex] GO:0071479 [cellular response to ionizing radiation] Show all	913 aa 101.1 kDa	No	0
INTS7-012 ENSP00000481102 ENST00000612340	A0A087WXK3 [Direct mapping] Integrator complex subunit 7 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		152 aa 17.6 kDa	No	0