Expression of SDE2 in cancer - Summary - The Human Protein Atlas

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SDE2

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	SDE2
Gene description	SDE2 telomere maintenance homolog (S. pombe)
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Nuclear expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Approved based on 3 antibodies. HPA028467 , HPA031255 , HPA031256
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

Pancreatic cancer

STAINING SUMMARY

HPA028467	HPA031255	HPA031256

GENE INFORMATION
Gene name	SDE2 (HGNC Symbol)
Synonyms	C1orf55, FLJ35382
Description	SDE2 telomere maintenance homolog (S. pombe) (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	q42.12
Chromosome location (bp)	225982702 - 225999331
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000143751 (version 83.38)
Entrez gene	163859
UniProt	Q6IQ49 (UniProt - Evidence at protein level)
neXtProt	NX_Q6IQ49
Antibodypedia	SDE2 antibodies

PROTEIN BROWSER

SDE2-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SDE2-001 ENSP00000272091 ENST00000272091	Q6IQ49 [Direct mapping] Protein SDE2 homolog Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] Show all	451 aa 49.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.