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WNT9A

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GENERAL INFORMATION

Gene name

 WNT9A

Gene description

 Wingless-type MMTV integration site family, member 9A

Protein class

 Plasma proteins
Predicted secreted proteins

Predicted localization

 Secreted

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Cell line enhanced (SCLC-21H, RH-30, SiHa, HaCaT)

Protein evidence

 Evidence at transcript level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (SCLC-21H, RH-30, SiHa, HaCaT)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 WNT9A (HGNC Symbol)

Synonyms

 WNT14

Description

 Wingless-type MMTV integration site family, member 9A (HGNC Symbol)

Entrez gene summary

 The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is expressed in gastric cancer cell lines. The protein encoded by this gene shows 75% amino acid identity to chicken Wnt14, which has been shown to play a central role in initiating synovial joint formation in the chick limb. This gene is clustered with another family member, WNT3A, in the chromosome 1q42 region. [provided by RefSeq, Jul 2008]

Chromosome

 1

Cytoband

 q42.13

Chromosome location (bp)

 227918656 - 227947898

Protein evidence

 Evidence at transcript level (all genes)

Ensembl

 ENSG00000143816 (version 83.38)

Entrez gene

 7483

UniProt

 O14904 (UniProt - Evidence at transcript level)

neXtProt

 NX_O14904

Antibodypedia

 WNT9A antibodies

PROTEIN BROWSER
WNT9A-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
WNT9A-001
ENSP00000272164
ENST00000272164
O14904 [Direct mapping]
Protein Wnt-9a
D9ZGG3 [Target identity:100%; Query identity:100%]
Protein Wnt
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   MEMSAT3 predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Show all
GO:0005102 [receptor binding]
GO:0005109 [frizzled binding]
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0005578 [proteinaceous extracellular matrix]
GO:0005615 [extracellular space]
GO:0007093 [mitotic cell cycle checkpoint]
GO:0007267 [cell-cell signaling]
GO:0007275 [multicellular organismal development]
GO:0008285 [negative regulation of cell proliferation]
GO:0016055 [Wnt signaling pathway]
GO:0030182 [neuron differentiation]
GO:0032331 [negative regulation of chondrocyte differentiation]
GO:0035115 [embryonic forelimb morphogenesis]
GO:0043154 [negative regulation of cysteine-type endopeptidase activity involved in apoptotic process]
GO:0045165 [cell fate commitment]
GO:0045597 [positive regulation of cell differentiation]
GO:0045880 [positive regulation of smoothened signaling pathway]
GO:0048704 [embryonic skeletal system morphogenesis]
GO:0048856 [anatomical structure development]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060548 [negative regulation of cell death]
GO:0061037 [negative regulation of cartilage development]
GO:0061072 [iris morphogenesis]
GO:0061303 [cornea development in camera-type eye]
GO:0070062 [extracellular exosome]
GO:0071300 [cellular response to retinoic acid]
GO:0072498 [embryonic skeletal joint development]
GO:0090090 [negative regulation of canonical Wnt signaling pathway]
Show all
 365 aa
40.3 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.