Fields »
ABOUT
HELP
BLOG
ARL8A

GENERAL INFORMATION

Gene name

 ARL8A

Gene description

 ADP-ribosylation factor-like 8A

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Cytoplasmic expression of varying intensity in most tissues.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Caution, targets protein from more than one gene.

Reliability score

 Approved based on 3 antibodies.
HPA038759 , HPA040515 , HPA045924
SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in colorectal cancer (unfavourable).
Colorectal cancer p<0.001
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA038759
HPA040515
HPA045924

GENE INFORMATION

Gene name

 ARL8A (HGNC Symbol)

Synonyms

 ARL10B, FLJ45195, Gie2

Description

 ADP-ribosylation factor-like 8A (HGNC Symbol)

Entrez gene summary

Chromosome

 1

Cytoband

 q32.1

Chromosome location (bp)

 202133404 - 202144743

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000143862 (version 83.38)

Entrez gene

 127829

UniProt

 Q96BM9 (UniProt - Evidence at protein level)

neXtProt

 NX_Q96BM9

Antibodypedia

 ARL8A antibodies

PROTEIN BROWSER
ARL8A-001
ARL8A-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ARL8A-001
ENSP00000272217
ENST00000272217
Q96BM9 [Direct mapping]
ADP-ribosylation factor-like protein 8A
A0A024R977 [Target identity:100%; Query identity:100%]
ADP-ribosylation factor-like 8A, isoform CRA_a
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003924 [GTPase activity]
GO:0005515 [protein binding]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0005737 [cytoplasm]
GO:0005765 [lysosomal membrane]
GO:0006886 [intracellular protein transport]
GO:0007059 [chromosome segregation]
GO:0007067 [mitotic nuclear division]
GO:0007264 [small GTPase mediated signal transduction]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0030496 [midbody]
GO:0031902 [late endosome membrane]
GO:0043014 [alpha-tubulin binding]
GO:0048487 [beta-tubulin binding]
GO:0051233 [spindle midzone]
GO:0051301 [cell division]
GO:0070062 [extracellular exosome]
Show all
 186 aa
21.4 kDa 		No 0
ARL8A-201
ENSP00000485023
ENST00000614750
A0A087X2J2 [Direct mapping]
ADP-ribosylation factor-like protein 8A
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0007264 [small GTPase mediated signal transduction]
Show all
 147 aa
16.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.