Expression of ABHD1 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

ABHD1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ABHD1
Gene description	Abhydrolase domain containing 1
Protein class	Predicted membrane proteins Predicted secreted proteins
Predicted localization	Membrane,Secreted
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enhanced (T-47d, U-266/70, U-266/84)
HPA (normal tissue):	Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

General membranous and cytoplasmic positivity.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining not consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA044390
	SHOW MORE

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA044390

GENE INFORMATION
Gene name	ABHD1 (HGNC Symbol)
Synonyms	FLJ36128, LABH1
Description	Abhydrolase domain containing 1 (HGNC Symbol)
Entrez gene summary	This gene is a member of the AB hydrolase superfamily and encodes a protein with an alpha/beta hydrolase fold. This domain is common to a number of hydrolytic enzymes of widely differing phylogenetic origins and catalytic functions. [provided by RefSeq, Jul 2008]
Chromosome	2
Cytoband	p23.3
Chromosome location (bp)	27123789 - 27130812
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000143994 (version 83.38)
Entrez gene	84696
UniProt	Q96SE0 (UniProt - Evidence at protein level)
neXtProt	NX_Q96SE0
Antibodypedia	ABHD1 antibodies

PROTEIN BROWSER

ABHD1-001	ABHD1-004	ABHD1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ABHD1-001 ENSP00000326491 ENST00000316470	Q96SE0 [Direct mapping] Abhydrolase domain-containing protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0008150 [biological_process] GO:0008152 [metabolic process] GO:0016021 [integral component of membrane] GO:0052689 [carboxylic ester hydrolase activity] Show all	405 aa 45.2 kDa	No	2
ABHD1-004 ENSP00000397522 ENST00000416071	C9J8C2 [Direct mapping] Abhydrolase domain-containing protein 1 Show all	SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins Show all		177 aa 19.2 kDa	Yes	0
ABHD1-201 ENSP00000481238 ENST00000621324	Q96SE0 [Direct mapping] Abhydrolase domain-containing protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0008150 [biological_process] GO:0008152 [metabolic process] GO:0016021 [integral component of membrane] GO:0052689 [carboxylic ester hydrolase activity] Show all	305 aa 33.8 kDa	No	2

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.