A few cases of prostate cancers displayed moderate to strong cytoplasmic immunoreactivity. Moderate staining was observed in cases of melanomas as well as a few thyroid and liver cancers. Remaining cancers were weakly stained or negative.
The GALNT13 protein is a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAcT; EC 184.108.40.206) family, which initiate O-linked glycosylation of mucins (see MUC3A, MIM 158371) by the initial transfer of N-acetylgalactosamine (GalNAc) with an alpha-linkage to a serine or threonine residue.[supplied by OMIM, Apr 2004]