Expression of GALNT13 in cancer - Summary - The Human Protein Atlas

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GALNT13

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	GALNT13
Gene description	Polypeptide N-acetylgalactosaminyltransferase 13
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enriched (glioma)
HPA (cell line):	Cell line enhanced (SH-SY5Y, WM-115)
HPA (normal tissue):	Group enriched (adrenal gland, cerebral cortex)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression mainly in processes of CNS.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining in cells/structures not annotated, view images.
Reliability score	Approved based on 1 antibody. HPA060775
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enriched (glioma)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA060775

GENE INFORMATION
Gene name	GALNT13 (HGNC Symbol)
Synonyms	GalNAc-T13, KIAA1918
Description	Polypeptide N-acetylgalactosaminyltransferase 13 (HGNC Symbol)
Entrez gene summary	The GALNT13 protein is a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAcT; EC 2.4.1.41) family, which initiate O-linked glycosylation of mucins (see MUC3A, MIM 158371) by the initial transfer of N-acetylgalactosamine (GalNAc) with an alpha-linkage to a serine or threonine residue.[supplied by OMIM, Apr 2004]
Chromosome	2
Cytoband
Chromosome location (bp)	153871913 - 154453849
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000144278 (version 83.38)
Entrez gene	114805
UniProt	Q8IUC8 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8IUC8
Antibodypedia	GALNT13 antibodies

PROTEIN BROWSER

GALNT13-001	GALNT13-002	GALNT13-004	GALNT13-005	GALNT13-006	GALNT13-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GALNT13-001 ENSP00000376570 ENST00000392825	Q8IUC8 [Direct mapping] Polypeptide N-acetylgalactosaminyltransferase 13 Show all	Enzymes ENZYME proteins Transferases MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0004653 [polypeptide N-acetylgalactosaminyltransferase activity] GO:0006493 [protein O-linked glycosylation] GO:0016021 [integral component of membrane] GO:0016266 [O-glycan processing] GO:0030246 [carbohydrate binding] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0046872 [metal ion binding] Show all	556 aa 64.1 kDa	No	0
GALNT13-002 ENSP00000414403 ENST00000434213	C9JLI4 [Direct mapping] Polypeptide N-acetylgalactosaminyltransferase 13 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		19 aa 2.3 kDa	No	0
GALNT13-004 ENSP00000396612 ENST00000453715	H7C0T6 [Direct mapping] Polypeptide N-acetylgalactosaminyltransferase 13 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		106 aa 12.3 kDa	No	0
GALNT13-005 ENSP00000387239 ENST00000409237	Q8IUC8 [Direct mapping] Polypeptide N-acetylgalactosaminyltransferase 13 Show all	Enzymes ENZYME proteins Transferases MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0004653 [polypeptide N-acetylgalactosaminyltransferase activity] GO:0006493 [protein O-linked glycosylation] GO:0016021 [integral component of membrane] GO:0016266 [O-glycan processing] GO:0030246 [carbohydrate binding] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0046872 [metal ion binding] Show all	561 aa 64.6 kDa	No	0
GALNT13-006 ENSP00000391469 ENST00000422126	H7BZU4 [Direct mapping] Polypeptide N-acetylgalactosaminyltransferase 13 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		45 aa 5.1 kDa	No	0
GALNT13-009 ENSP00000406237 ENST00000450838	H7C2I5 [Direct mapping] Polypeptide N-acetylgalactosaminyltransferase 13 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		142 aa 16.4 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.