Expression of SLC22A14 in cancer - Summary - The Human Protein Atlas

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SLC22A14

TISSUE

CELL

PATHOLOGY

GENERAL INFORMATION
Gene name	SLC22A14
Gene description	Solute carrier family 22, member 14
Protein class	Predicted membrane proteins Transporters
Predicted localization	Membrane
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Not detected
HPA (normal tissue):	Tissue enriched (testis)

Protein evidence

Evidence at transcript level

ANTIBODY IHC RELIABILITY
Reliability score	Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION
Pending cancer tissue analysis
STAINING SUMMARY

GENE INFORMATION
Gene name	SLC22A14 (HGNC Symbol)
Synonyms	OCTL2, ORCTL4
Description	Solute carrier family 22, member 14 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the organic-cation transporter family. It is located in a gene cluster with another member of the family, organic cation transporter like 3. The encoded protein is a transmembrane protein which is thought to transport small molecules and since this protein is conserved among several species, it is suggested to have a fundamental role in mammalian systems. [provided by RefSeq, Jul 2008]
Chromosome	3
Cytoband	p22.2
Chromosome location (bp)	38282294 - 38318575
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000144671 (version 83.38)
Entrez gene	9389
UniProt	Q9Y267 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9Y267
Antibodypedia	SLC22A14 antibodies

PROTEIN BROWSER

SLC22A14-001	SLC22A14-002	SLC22A14-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC22A14-001 ENSP00000273173 ENST00000273173	Q9Y267 [Direct mapping] Solute carrier family 22 member 14 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Show all	GO:0005887 [integral component of plasma membrane] GO:0015101 [organic cation transmembrane transporter activity] GO:0015695 [organic cation transport] GO:0016021 [integral component of membrane] GO:0022857 [transmembrane transporter activity] GO:0022891 [substrate-specific transmembrane transporter activity] GO:0055085 [transmembrane transport] Show all	594 aa 66.7 kDa	No	>9
SLC22A14-002 ENSP00000396283 ENST00000448498	Q9Y267 [Direct mapping] Solute carrier family 22 member 14 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Show all	GO:0005887 [integral component of plasma membrane] GO:0015101 [organic cation transmembrane transporter activity] GO:0015695 [organic cation transport] GO:0016021 [integral component of membrane] GO:0022857 [transmembrane transporter activity] GO:0022891 [substrate-specific transmembrane transporter activity] GO:0055085 [transmembrane transport] Show all	594 aa 66.7 kDa	No	>9
SLC22A14-005 ENSP00000442528 ENST00000466887	F5H7H1 [Direct mapping] Solute carrier family 22 member 14 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] GO:0022857 [transmembrane transporter activity] GO:0055085 [transmembrane transport] Show all	119 aa 13.5 kDa	No	2

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.