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ABHD10

GENERAL INFORMATION

Gene name

 ABHD10

Gene description

 Abhydrolase domain containing 10

Protein class

 Enzymes
Predicted secreted proteins

Predicted localization

 Secreted

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 General granular cytoplasmic expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

 Supported based on 2 antibodies.
HPA036991 , HPA036992
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
N/A
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Gallbladder

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 ABHD10 (HGNC Symbol)

Synonyms

 FLJ11342

Description

 Abhydrolase domain containing 10 (HGNC Symbol)

Entrez gene summary

 This gene encodes a mitochondrially-localized enzyme that acts in liver cells as a hydrolase. The encoded protein removes glucuronide from mycophenolic acid acyl-glucuronide. There is a pseudogene for this gene on chromosome 6. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

Chromosome

 3

Cytoband

 q13.2

Chromosome location (bp)

 111979010 - 111993363

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000144827 (version 83.38)

Entrez gene

 55347

UniProt

 Q9NUJ1 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9NUJ1

Antibodypedia

 ABHD10 antibodies

PROTEIN BROWSER
ABHD10-001
ABHD10-005

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ABHD10-001
ENSP00000273359
ENST00000273359
Q9NUJ1 [Direct mapping]
Mycophenolic acid acyl-glucuronide esterase, mitochondrial
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Enzymes
   ENZYME proteins
   Hydrolases
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004553 [hydrolase activity, hydrolyzing O-glycosyl compounds]
GO:0005739 [mitochondrion]
GO:0005759 [mitochondrial matrix]
GO:0005829 [cytosol]
GO:0006805 [xenobiotic metabolic process]
GO:0019391 [glucuronoside catabolic process]
GO:0044281 [small molecule metabolic process]
GO:0052695 [cellular glucuronidation]
Show all
 306 aa
33.9 kDa 		Yes 0
ABHD10-005
ENSP00000418973
ENST00000494817
Q9NUJ1 [Direct mapping]
Mycophenolic acid acyl-glucuronide esterase, mitochondrial
Show all
Enzymes
   ENZYME proteins
   Hydrolases
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004553 [hydrolase activity, hydrolyzing O-glycosyl compounds]
GO:0005739 [mitochondrion]
GO:0005759 [mitochondrial matrix]
GO:0005829 [cytosol]
GO:0006805 [xenobiotic metabolic process]
GO:0019391 [glucuronoside catabolic process]
GO:0044281 [small molecule metabolic process]
GO:0052695 [cellular glucuronidation]
Show all
 205 aa
22.1 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.