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Several liver, pancreatic, breast, ovarian and testicular cancers displayed moderate cytoplasmic positivity. Remaining malignancies were weakly stained or negative.
Malignant cells generally showed weak or moderate cytoplasmic staining.
GENE INFORMATION
Gene name
GC (HGNC Symbol)
Synonyms
DBP, hDBP, VDBP
Description
Group-specific component (vitamin D binding protein) (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]
Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)