Expression of GIN1 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

GIN1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	GIN1
Gene description	Gypsy retrotransposon integrase 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic and/or nuclear expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA037402
	SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

Pancreatic cancer

STAINING SUMMARY

HPA037402

GENE INFORMATION
Gene name	GIN1 (HGNC Symbol)
Synonyms	FLJ20125, GIN-1, TGIN1, ZH2C2
Description	Gypsy retrotransposon integrase 1 (HGNC Symbol)
Entrez gene summary
Chromosome	5
Cytoband	q21.1
Chromosome location (bp)	103086000 - 103120151
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000145723 (version 83.38)
Entrez gene	54826
UniProt	Q9NXP7 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9NXP7
Antibodypedia	GIN1 antibodies

PROTEIN BROWSER

GIN1-001	GIN1-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GIN1-001 ENSP00000381970 ENST00000399004	Q9NXP7 [Direct mapping] Gypsy retrotransposon integrase-like protein 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0015074 [DNA integration] GO:0032197 [transposition, RNA-mediated] Show all	522 aa 59.8 kDa	No	0
GIN1-003 ENSP00000427162 ENST00000508629	Q9NXP7 [Direct mapping] Gypsy retrotransposon integrase-like protein 1 Show all	MEMSAT3 predicted membrane proteins Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0015074 [DNA integration] GO:0032197 [transposition, RNA-mediated] Show all	222 aa 25.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.