Expression of BOD1 in cancer - Summary - The Human Protein Atlas

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BOD1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	BOD1
Gene description	Biorientation of chromosomes in cell division 1
Protein class	Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

General cytoplasmic and membranous expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Caution, targets protein from more than one gene.
Reliability score	Uncertain based on 1 antibody. HPA036293
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PROGNOSTIC SUMMARY
Prognostic marker in liver cancer (unfavourable) and head and neck cancer (unfavourable).
Liver cancer p<0.001 Head and neck cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA036293

GENE INFORMATION
Gene name	BOD1 (HGNC Symbol)
Synonyms	FAM44B
Description	Biorientation of chromosomes in cell division 1 (HGNC Symbol)
Entrez gene summary
Chromosome	5
Cytoband	q35.2
Chromosome location (bp)	173607514 - 173616660
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000145919 (version 83.38)
Entrez gene	91272
UniProt	Q96IK1 (UniProt - Evidence at protein level)
neXtProt	NX_Q96IK1
Antibodypedia	BOD1 antibodies

PROTEIN BROWSER

BOD1-001	BOD1-002	BOD1-003	BOD1-005	BOD1-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
BOD1-001 ENSP00000309644 ENST00000311086	Q96IK1 [Direct mapping] Biorientation of chromosomes in cell division protein 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000777 [condensed chromosome kinetochore] GO:0005737 [cytoplasm] GO:0005815 [microtubule organizing center] GO:0007067 [mitotic nuclear division] GO:0051301 [cell division] Show all	185 aa 19.2 kDa	No	0
BOD1-002 ENSP00000285908 ENST00000285908	Q96IK1 [Direct mapping] Biorientation of chromosomes in cell division protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000777 [condensed chromosome kinetochore] GO:0005737 [cytoplasm] GO:0005815 [microtubule organizing center] GO:0007067 [mitotic nuclear division] GO:0051301 [cell division] Show all	129 aa 13.3 kDa	No	0
BOD1-003 ENSP00000417641 ENST00000462674	C9J8U9 [Direct mapping] Biorientation of chromosomes in cell division protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		42 aa 4.8 kDa	No	0
BOD1-005 ENSP00000420337 ENST00000480951	C9JNZ5 [Direct mapping] Biorientation of chromosomes in cell division protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		85 aa 8 kDa	No	0
BOD1-006 ENSP00000420005 ENST00000477985	H7C5I4 [Direct mapping] Biorientation of chromosomes in cell division protein 1 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all		118 aa 12.3 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.