Tissue expression of KCNMB1 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	KCNMB1
Gene description	Potassium channel subfamily M regulatory beta subunit 1
Protein class	Predicted membrane proteins Transporters
Predicted localization	Membrane
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (seminal vesicle, smooth muscle)
GTEx:	Tissue enhanced (endometrium)
FANTOM5:	Mixed

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (seminal vesicle, smooth muscle)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (endometrium)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Mixed

GENE INFORMATION
Gene name	KCNMB1 (HGNC Symbol)
Synonyms	hslo-beta
Description	Potassium channel subfamily M regulatory beta subunit 1 (HGNC Symbol)
Entrez gene summary	MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the product of this gene, the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. [provided by RefSeq, Jul 2008]
Chromosome	5
Cytoband	q35.1
Chromosome location (bp)	170374671 - 170389677
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000145936 (version 83.38)
Entrez gene	3779
UniProt	Q16558 (UniProt - Evidence at protein level)
neXtProt	NX_Q16558
Antibodypedia	KCNMB1 antibodies

PROTEIN BROWSER

KCNMB1-001	KCNMB1-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
KCNMB1-001 ENSP00000274629 ENST00000274629	Q16558 [Direct mapping] Calcium-activated potassium channel subunit beta-1 Show all	Transporters Accessory Factors Involved in Transport Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0005513 [detection of calcium ion] GO:0005886 [plasma membrane] GO:0006813 [potassium ion transport] GO:0007268 [synaptic transmission] GO:0007596 [blood coagulation] GO:0008076 [voltage-gated potassium channel complex] GO:0015269 [calcium-activated potassium channel activity] GO:0015459 [potassium channel regulator activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0051592 [response to calcium ion] GO:0071805 [potassium ion transmembrane transport] Show all	191 aa 21.8 kDa	No	2
KCNMB1-002 ENSP00000427940 ENST00000521859	Q16558 [Direct mapping] Calcium-activated potassium channel subunit beta-1 Show all	Transporters Accessory Factors Involved in Transport Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005513 [detection of calcium ion] GO:0005886 [plasma membrane] GO:0006813 [potassium ion transport] GO:0007268 [synaptic transmission] GO:0007596 [blood coagulation] GO:0008076 [voltage-gated potassium channel complex] GO:0015269 [calcium-activated potassium channel activity] GO:0016020 [membrane] GO:0071805 [potassium ion transmembrane transport] Show all	130 aa 14.9 kDa	No	1