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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

Category

Score

Score

Score

Antibodies

Column

 
 
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FAM217A
  • TISSUE

  • CELL

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PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

GENERAL INFORMATION

Gene name

FAM217A

Gene description

Family with sequence similarity 217, member A

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

3
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):Not detected
HPA (cell line):Not detected
HPA (normal tissue):Tissue enriched (testis)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY

Data reliability
description

RNA-based expert annotation gave inconclusive results. Pending external verification.

Reliability score

Uncertain based on 1 antibody.
HPA035455
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PROGNOSTIC SUMMARY

Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW

TCGA dataset
RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

HPA035455

Cancer

Cancer staining

Breast cancer
Carcinoid
Cervical cancer
Colorectal cancer
Endometrial cancer
Glioma
Head and neck cancer
Liver cancer
Lung cancer
Lymphoma
 

Cancer

Cancer staining

Melanoma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cancer
Skin cancer
Stomach cancer
Testis cancer
Thyroid cancer
Urothelial cancer

Staining summary

Most malignant tissues were weakly stained or negative. Several malignant melanomas, colorectal, skin, pancreatic and female genital cancers displayed moderate immunoreactivity.

GENE INFORMATION

Gene name

FAM217A (HGNC Symbol)

Synonyms

C6orf146, MGC43581

Description

Family with sequence similarity 217, member A (HGNC Symbol)

Entrez gene summary

Chromosome

6

Cytoband

p25.2

Chromosome location (bp)

4049434 - 4087344

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000145975 (version 83.38)

Entrez gene

222826

UniProt

Q8IXS0 (UniProt - Evidence at transcript level)

neXtProt

NX_Q8IXS0

Antibodypedia

FAM217A antibodies

PROTEIN BROWSER

FAM217A-001
FAM217A-006
FAM217A-007

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FAM217A-001
ENSP00000274673
ENST00000274673
Q8IXS0 [Direct mapping]
Protein FAM217A
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Predicted intracellular proteins
Show all
508 aa
57.4 kDa
No 0
FAM217A-006
ENSP00000418500
ENST00000498677
C9J5H0 [Direct mapping]
Protein FAM217A
Show all
Predicted intracellular proteins
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48 aa
5.4 kDa
No 0
FAM217A-007
ENSP00000418339
ENST00000492651
C9J6U0 [Direct mapping]
Protein FAM217A
Show all
Predicted intracellular proteins
Show all
32 aa
3.6 kDa
No 0

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