Expression of KAAG1 in cancer - Summary - The Human Protein Atlas

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KAAG1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	KAAG1
Gene description	Kidney associated antigen 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Group enriched (CACO-2, EFO-21, HEK93, Hep G2, RPTEC TERT1)
HPA (normal tissue):	Not detected

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Expression mainly in seminiferous ducts in testis.

ANTIBODY IHC RELIABILITY
Data reliability description	Presumed off target binding observed and disregarded. External characterization data supports antibody staining pattern while RNA data does not. Pending retesting.
Reliability score	Approved based on 1 antibody. HPA036021
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA036021

GENE INFORMATION
Gene name	KAAG1 (HGNC Symbol)
Synonyms	RU2, RU2AS
Description	Kidney associated antigen 1 (HGNC Symbol)
Entrez gene summary
Chromosome	6
Cytoband	p22.3
Chromosome location (bp)	24356903 - 24358284
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000146049 (version 83.38)
Entrez gene	353219
UniProt	Q9UBP8 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9UBP8
Antibodypedia	KAAG1 antibodies

PROTEIN BROWSER

KAAG1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
KAAG1-001 ENSP00000274766 ENST00000274766	Q9UBP8 [Direct mapping] Kidney-associated antigen 1 Show all	Predicted intracellular proteins Show all	GO:0005575 [cellular_component] GO:0006955 [immune response] Show all	84 aa 9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.