Expression of IRAK1BP1 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

IRAK1BP1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	IRAK1BP1
Gene description	Interleukin-1 receptor-associated kinase 1 binding protein 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Mixed
HPA (normal tissue):	Tissue enriched (bone marrow)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 2 antibodies. HPA035742 , HPA035743
	SHOW MORE

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA035742	HPA035743

GENE INFORMATION
Gene name	IRAK1BP1 (HGNC Symbol)
Synonyms	AIP70, SIMPL
Description	Interleukin-1 receptor-associated kinase 1 binding protein 1 (HGNC Symbol)
Entrez gene summary
Chromosome	6
Cytoband	q14.1
Chromosome location (bp)	78867472 - 78946440
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000146243 (version 83.38)
Entrez gene	134728
UniProt	Q5VVH5 (UniProt - Evidence at protein level)
neXtProt	NX_Q5VVH5
Antibodypedia	IRAK1BP1 antibodies

PROTEIN BROWSER

IRAK1BP1-001	IRAK1BP1-002	IRAK1BP1-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
IRAK1BP1-001 ENSP00000358956 ENST00000369940	Q5VVH5 [Direct mapping] Interleukin-1 receptor-associated kinase 1-binding protein 1 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0007249 [I-kappaB kinase/NF-kappaB signaling] Show all	260 aa 29.1 kDa	No	0
IRAK1BP1-002 ENSP00000475395 ENST00000606929	U3KQ00 [Direct mapping] Interleukin-1 receptor-associated kinase 1-binding protein 1 Show all	Predicted intracellular proteins Show all		44 aa 4.8 kDa	No	0
IRAK1BP1-003 ENSP00000475503 ENST00000607739	U3KQ34 [Direct mapping] Interleukin-1 receptor-associated kinase 1-binding protein 1 Show all	Predicted intracellular proteins Show all		192 aa 21.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.