Expression of ABRACL in cancer - Summary - The Human Protein Atlas

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ABRACL

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ABRACL
Gene description	ABRA C-terminal like
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Mixed
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in a majority of the tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA030217
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PROGNOSTIC SUMMARY
Prognostic marker in urothelial cancer (favourable).
Urothelial cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA030217

GENE INFORMATION
Gene name	ABRACL (HGNC Symbol)
Synonyms	C6orf115, Costars, HSPC280, PRO2013
Description	ABRA C-terminal like (HGNC Symbol)
Entrez gene summary
Chromosome	6
Cytoband	q24.1
Chromosome location (bp)	139028682 - 139043302
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000146386 (version 83.38)
Entrez gene	58527
UniProt	Q9P1F3 (UniProt - Evidence at protein level)
neXtProt	NX_Q9P1F3
Antibodypedia	ABRACL antibodies

PROTEIN BROWSER

ABRACL-001	ABRACL-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ABRACL-001 ENSP00000356632 ENST00000367660	Q9P1F3 [Direct mapping] Costars family protein ABRACL Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all		81 aa 9.1 kDa	No	0
ABRACL-002 ENSP00000418406 ENST00000461027	Q5SZC9 [Direct mapping] Costars family protein ABRACL Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		67 aa 7.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.