Expression of C7orf50 in cancer - Summary - The Human Protein Atlas

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C7orf50

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	C7orf50
Gene description	Chromosome 7 open reading frame 50
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic and nuclear expresion in most cell types.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA052281
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PROGNOSTIC SUMMARY
Prognostic marker in pancreatic cancer (favourable).
Pancreatic cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA052281

GENE INFORMATION
Gene name	C7orf50 (HGNC Symbol)
Synonyms	MGC11257, YCR016W
Description	Chromosome 7 open reading frame 50 (HGNC Symbol)
Entrez gene summary
Chromosome	7
Cytoband	p22.3
Chromosome location (bp)	996986 - 1138260
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000146540 (version 83.38)
Entrez gene	84310
UniProt	Q9BRJ6 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BRJ6
Antibodypedia	C7orf50 antibodies

PROTEIN BROWSER

C7orf50-001	C7orf50-002	C7orf50-003	C7orf50-005	C7orf50-007	C7orf50-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C7orf50-001 ENSP00000350011 ENST00000357429	Q9BRJ6 [Direct mapping] Uncharacterized protein C7orf50 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0044822 [poly(A) RNA binding] Show all	194 aa 22.1 kDa	No	0
C7orf50-002 ENSP00000380286 ENST00000397098	Q9BRJ6 [Direct mapping] Uncharacterized protein C7orf50 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0044822 [poly(A) RNA binding] Show all	194 aa 22.1 kDa	No	0
C7orf50-003 ENSP00000407380 ENST00000412051	H7C2R9 [Direct mapping] Uncharacterized protein C7orf50 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		179 aa 20.4 kDa	No	0
C7orf50-005 ENSP00000396542 ENST00000444428	H7C0T1 [Direct mapping] Uncharacterized protein C7orf50 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		162 aa 18.7 kDa	No	0
C7orf50-007 ENSP00000420130 ENST00000491163	C9JQV0 [Direct mapping] Uncharacterized protein C7orf50 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		192 aa 21.9 kDa	No	0
C7orf50-201 ENSP00000380288 ENST00000397100	Q9BRJ6 [Direct mapping] Uncharacterized protein C7orf50 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0044822 [poly(A) RNA binding] Show all	194 aa 22.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.