Expression of C7orf26 in cancer - Summary - The Human Protein Atlas

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C7orf26

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	C7orf26
Gene description	Chromosome 7 open reading frame 26
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic and nuclear expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data.
Reliability score	Uncertain based on 1 antibody. HPA052175
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PROGNOSTIC SUMMARY
Prognostic marker in pancreatic cancer (favourable).
Pancreatic cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA052175

GENE INFORMATION
Gene name	C7orf26 (HGNC Symbol)
Synonyms	MGC2718
Description	Chromosome 7 open reading frame 26 (HGNC Symbol)
Entrez gene summary
Chromosome	7
Cytoband	p22.1
Chromosome location (bp)	6590017 - 6608726
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000146576 (version 83.38)
Entrez gene	79034
UniProt	Q96N11 (UniProt - Evidence at transcript level)
neXtProt	NX_Q96N11
Antibodypedia	C7orf26 antibodies

PROTEIN BROWSER

C7orf26-001	C7orf26-002	C7orf26-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C7orf26-001 ENSP00000340220 ENST00000344417	Q96N11 [Direct mapping] Uncharacterized protein C7orf26 Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all		449 aa 50 kDa	No	0
C7orf26-002 ENSP00000351974 ENST00000359073	Q96N11 [Direct mapping] Uncharacterized protein C7orf26 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		352 aa 39 kDa	No	0
C7orf26-007 ENSP00000390166 ENST00000445375	H7BZK9 [Direct mapping] Uncharacterized protein C7orf26 Show all	SPOCTOPUS predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		149 aa 16.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.