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Most malignant cells showed moderate cytoplasmic and/or nucleolar immunoreactivity. A few cases of squamous cell carcinomas of skin along with occasional adenocarcinomas of lung, renal, pancreatic and colorectal cancers were strongly stained.
GENE INFORMATION
Gene name
CNPY1
Synonyms
Description
Canopy FGF signaling regulator 1 (HGNC Symbol)
Entrez gene summary
Cnpy1 is expressed in the midbrain-hindbrain (MHB) boundary in zebrafish, binds FGFR1 (MIM 136350), and plays a role in FGF signaling (Hirate and Okamoto, 2006 [PubMed 16488878]).[supplied by OMIM, Dec 2008]