Expression of ASB10 in cancer - Summary - The Human Protein Atlas

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ASB10

TISSUE

CELL

PATHOLOGY

GENERAL INFORMATION
Gene name	ASB10
Gene description	Ankyrin repeat and SOCS box containing 10
Protein class	Disease related genes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Not detected
HPA (normal tissue):	Tissue enriched (skeletal muscle)

Protein evidence

Evidence at protein level

ANTIBODY IHC RELIABILITY
Reliability score	Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION
Pending cancer tissue analysis
STAINING SUMMARY

GENE INFORMATION
Gene name	ASB10 (HGNC Symbol)
Synonyms	GLC1F
Description	Ankyrin repeat and SOCS box containing 10 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. The SOCS box serves to couple suppressor of cytokine signaling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2008]
Chromosome	7
Cytoband	q36.1
Chromosome location (bp)	151175698 - 151187832
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000146926 (version 83.38)
Entrez gene	136371
UniProt	Q8WXI3 (UniProt - Evidence at protein level)
neXtProt	NX_Q8WXI3
Antibodypedia	ASB10 antibodies

PROTEIN BROWSER

ASB10-001	ASB10-002	ASB10-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ASB10-001 ENSP00000391137 ENST00000420175	Q8WXI3 [Direct mapping] Ankyrin repeat and SOCS box protein 10 Show all	Predicted intracellular proteins Disease related genes Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0016567 [protein ubiquitination] GO:0035556 [intracellular signal transduction] Show all	467 aa 50.9 kDa	No	0
ASB10-002 ENSP00000275838 ENST00000275838	Q8WXI3 [Direct mapping] Ankyrin repeat and SOCS box protein 10 A0A090N8I2 [Target identity:100%; Query identity:100%] Ankyrin repeat and SOCS box-containing 10; Ankyrin repeat and SOCS box-containing 10, isoform CRA_c Show all	Predicted intracellular proteins Disease related genes Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0016567 [protein ubiquitination] GO:0035556 [intracellular signal transduction] Show all	429 aa 46.6 kDa	No	0
ASB10-003 ENSP00000367098 ENST00000377867	Q8WXI3 [Direct mapping] Ankyrin repeat and SOCS box protein 10 Show all	Predicted intracellular proteins Disease related genes Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0016567 [protein ubiquitination] GO:0035556 [intracellular signal transduction] Show all	452 aa 49.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.