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SLC26A7

GENERAL INFORMATION

Gene name

 SLC26A7

Gene description

 Solute carrier family 26 (anion exchanger), member 7

Protein class

 Predicted membrane proteins

Predicted localization

 Membrane

Number of transcripts

 7
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Group enriched (renal cancer, thyroid cancer)
HPA (cell line):Not detected
HPA (normal tissue):Tissue enriched (thyroid gland)

Protein evidence

 Evidence at transcript level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Group enriched (renal cancer, thyroid cancer)

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 SLC26A7 (HGNC Symbol)

Synonyms

 SUT2

Description

 Solute carrier family 26 (anion exchanger), member 7 (HGNC Symbol)

Entrez gene summary

 This gene is one member of a family of sulfate/anion transporter genes. Family members are well conserved in gene structure and protein length yet have markedly different tissue expression patterns. This gene has abundant and specific expression in the kidney. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Aug 2013]

Chromosome

 8

Cytoband

 q21.3

Chromosome location (bp)

 91209494 - 91398152

Protein evidence

 Evidence at transcript level (all genes)

Ensembl

 ENSG00000147606 (version 83.38)

Entrez gene

 115111

UniProt

 Q8TE54 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q8TE54

Antibodypedia

 SLC26A7 antibodies

PROTEIN BROWSER
SLC26A7-001
SLC26A7-003
SLC26A7-004
SLC26A7-006
SLC26A7-007
SLC26A7-201
SLC26A7-202

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SLC26A7-001
ENSP00000428849
ENST00000523719
Q8TE54 [Direct mapping]
Anion exchange transporter
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   >9TM proteins predicted by MDM
Show all
GO:0005254 [chloride channel activity]
GO:0005737 [cytoplasm]
GO:0005768 [endosome]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006811 [ion transport]
GO:0006820 [anion transport]
GO:0006821 [chloride transport]
GO:0008271 [secondary active sulfate transmembrane transporter activity]
GO:0008272 [sulfate transport]
GO:0015106 [bicarbonate transmembrane transporter activity]
GO:0015116 [sulfate transmembrane transporter activity]
GO:0015301 [anion:anion antiporter activity]
GO:0015701 [bicarbonate transport]
GO:0016021 [integral component of membrane]
GO:0016323 [basolateral plasma membrane]
GO:0019531 [oxalate transmembrane transporter activity]
GO:0019532 [oxalate transport]
GO:0042391 [regulation of membrane potential]
GO:0051453 [regulation of intracellular pH]
GO:0055038 [recycling endosome membrane]
GO:0055085 [transmembrane transport]
GO:0098656 [anion transmembrane transport]
GO:1902358 [sulfate transmembrane transport]
GO:1902476 [chloride transmembrane transport]
Show all
 656 aa
72.2 kDa 		No >9
SLC26A7-003
ENSP00000276609
ENST00000276609
Q8TE54 [Direct mapping]
Anion exchange transporter
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   >9TM proteins predicted by MDM
Show all
GO:0005254 [chloride channel activity]
GO:0005737 [cytoplasm]
GO:0005768 [endosome]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006811 [ion transport]
GO:0006820 [anion transport]
GO:0006821 [chloride transport]
GO:0008271 [secondary active sulfate transmembrane transporter activity]
GO:0008272 [sulfate transport]
GO:0015106 [bicarbonate transmembrane transporter activity]
GO:0015116 [sulfate transmembrane transporter activity]
GO:0015301 [anion:anion antiporter activity]
GO:0015701 [bicarbonate transport]
GO:0016021 [integral component of membrane]
GO:0016323 [basolateral plasma membrane]
GO:0019531 [oxalate transmembrane transporter activity]
GO:0019532 [oxalate transport]
GO:0042391 [regulation of membrane potential]
GO:0051453 [regulation of intracellular pH]
GO:0055038 [recycling endosome membrane]
GO:0055085 [transmembrane transport]
GO:0098656 [anion transmembrane transport]
GO:1902358 [sulfate transmembrane transport]
GO:1902476 [chloride transmembrane transport]
Show all
 656 aa
72.2 kDa 		No >9
SLC26A7-004
ENSP00000309504
ENST00000309536
Q8TE54 [Direct mapping]
Anion exchange transporter
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   >9TM proteins predicted by MDM
Show all
GO:0001696 [gastric acid secretion]
GO:0005253 [anion channel activity]
GO:0005254 [chloride channel activity]
GO:0005737 [cytoplasm]
GO:0005768 [endosome]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006811 [ion transport]
GO:0006820 [anion transport]
GO:0006821 [chloride transport]
GO:0008271 [secondary active sulfate transmembrane transporter activity]
GO:0008272 [sulfate transport]
GO:0015106 [bicarbonate transmembrane transporter activity]
GO:0015116 [sulfate transmembrane transporter activity]
GO:0015301 [anion:anion antiporter activity]
GO:0015701 [bicarbonate transport]
GO:0016021 [integral component of membrane]
GO:0016323 [basolateral plasma membrane]
GO:0019531 [oxalate transmembrane transporter activity]
GO:0019532 [oxalate transport]
GO:0042391 [regulation of membrane potential]
GO:0051453 [regulation of intracellular pH]
GO:0055038 [recycling endosome membrane]
GO:0055085 [transmembrane transport]
GO:0098656 [anion transmembrane transport]
GO:1902358 [sulfate transmembrane transport]
GO:1902476 [chloride transmembrane transport]
Show all
 663 aa
73 kDa 		No >9
SLC26A7-006
ENSP00000428881
ENST00000522862
E5RFH2 [Direct mapping]
Anion exchange transporter
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   5TM proteins predicted by MDM
Show all
GO:0001696 [gastric acid secretion]
GO:0008271 [secondary active sulfate transmembrane transporter activity]
GO:0008272 [sulfate transport]
GO:0015116 [sulfate transmembrane transporter activity]
GO:0016021 [integral component of membrane]
GO:0016323 [basolateral plasma membrane]
GO:1902358 [sulfate transmembrane transport]
Show all
 207 aa
22.6 kDa 		No 5
SLC26A7-007
ENSP00000428747
ENST00000520818
H0YB61 [Direct mapping]
Anion exchange transporter
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   6TM proteins predicted by MDM
Show all
GO:0001696 [gastric acid secretion]
GO:0008271 [secondary active sulfate transmembrane transporter activity]
GO:0008272 [sulfate transport]
GO:0015116 [sulfate transmembrane transporter activity]
GO:0016021 [integral component of membrane]
GO:0016323 [basolateral plasma membrane]
GO:1902358 [sulfate transmembrane transport]
Show all
 237 aa
25.6 kDa 		No 6
SLC26A7-201
ENSP00000482686
ENST00000617078
A0A087WZI7 [Direct mapping]
Anion exchange transporter
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   4TM proteins predicted by MDM
Show all
GO:0001696 [gastric acid secretion]
GO:0008271 [secondary active sulfate transmembrane transporter activity]
GO:0008272 [sulfate transport]
GO:0015116 [sulfate transmembrane transporter activity]
GO:0016021 [integral component of membrane]
GO:0016323 [basolateral plasma membrane]
GO:1902358 [sulfate transmembrane transport]
Show all
 355 aa
39.2 kDa 		No 4
SLC26A7-202
ENSP00000482549
ENST00000617233
Q8TE54 [Direct mapping]
Anion exchange transporter
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   >9TM proteins predicted by MDM
Show all
GO:0005254 [chloride channel activity]
GO:0005737 [cytoplasm]
GO:0005768 [endosome]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006811 [ion transport]
GO:0006820 [anion transport]
GO:0006821 [chloride transport]
GO:0008271 [secondary active sulfate transmembrane transporter activity]
GO:0008272 [sulfate transport]
GO:0015106 [bicarbonate transmembrane transporter activity]
GO:0015116 [sulfate transmembrane transporter activity]
GO:0015301 [anion:anion antiporter activity]
GO:0015701 [bicarbonate transport]
GO:0016021 [integral component of membrane]
GO:0016323 [basolateral plasma membrane]
GO:0019531 [oxalate transmembrane transporter activity]
GO:0019532 [oxalate transport]
GO:0042391 [regulation of membrane potential]
GO:0051453 [regulation of intracellular pH]
GO:0055038 [recycling endosome membrane]
GO:0055085 [transmembrane transport]
GO:0098656 [anion transmembrane transport]
GO:1902358 [sulfate transmembrane transport]
GO:1902476 [chloride transmembrane transport]
Show all
 656 aa
72.2 kDa 		No >9

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.