Expression of FAM83A in cancer - Summary - The Human Protein Atlas

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FAM83A

TISSUE

CELL

PATHOLOGY

GENERAL INFORMATION
Gene name	FAM83A
Gene description	Family with sequence similarity 83, member A
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enhanced (head and neck cancer)
HPA (cell line):	Cell line enhanced (A-431, hTCEpi, K-562)
HPA (normal tissue):	Tissue enriched (esophagus)

Protein evidence

Evidence at protein level

ANTIBODY IHC RELIABILITY
Reliability score	Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Prognostic marker in lung cancer (unfavourable), pancreatic cancer (unfavourable) and endometrial cancer (unfavourable).
Lung cancer p<0.001 Pancreatic cancer p<0.001 Endometrial cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enhanced (head and neck cancer)

PROTEIN EXPRESSION
Pending cancer tissue analysis
STAINING SUMMARY

GENE INFORMATION
Gene name	FAM83A (HGNC Symbol)
Synonyms	BJ-TSA-9, MGC14128
Description	Family with sequence similarity 83, member A (HGNC Symbol)
Entrez gene summary
Chromosome	8
Cytoband	q24.13
Chromosome location (bp)	123178960 - 123210079
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000147689 (version 83.38)
Entrez gene	84985
UniProt	Q86UY5 (UniProt - Evidence at protein level)
neXtProt	NX_Q86UY5
Antibodypedia	FAM83A antibodies

PROTEIN BROWSER

FAM83A-001	FAM83A-002	FAM83A-003	FAM83A-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAM83A-001 ENSP00000428876 ENST00000518448	Q86UY5 [Direct mapping] Protein FAM83A Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0007173 [epidermal growth factor receptor signaling pathway] GO:0008283 [cell proliferation] GO:0019901 [protein kinase binding] GO:0036312 [phosphatidylinositol 3-kinase regulatory subunit binding] Show all	434 aa 47.5 kDa	No	0
FAM83A-002 ENSP00000276699 ENST00000276699	Q86UY5 [Direct mapping] Protein FAM83A Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0007173 [epidermal growth factor receptor signaling pathway] GO:0008283 [cell proliferation] GO:0019901 [protein kinase binding] GO:0036312 [phosphatidylinositol 3-kinase regulatory subunit binding] Show all	367 aa 40.6 kDa	No	0
FAM83A-003 ENSP00000427979 ENST00000522648	Q86UY5 [Direct mapping] Protein FAM83A Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0007173 [epidermal growth factor receptor signaling pathway] GO:0008283 [cell proliferation] GO:0019901 [protein kinase binding] GO:0036312 [phosphatidylinositol 3-kinase regulatory subunit binding] Show all	294 aa 32.2 kDa	No	0
FAM83A-201 ENSP00000445218 ENST00000536633	Q86UY5 [Direct mapping] Protein FAM83A Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0007173 [epidermal growth factor receptor signaling pathway] GO:0008283 [cell proliferation] GO:0019901 [protein kinase binding] GO:0036312 [phosphatidylinositol 3-kinase regulatory subunit binding] Show all	367 aa 40.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.