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Liver cancers and some cases of melanoma, pancreatic, urothelial and endometrial cancers showed moderate cytoplasmic stained. Remaining cancers were weakly stained or negative.
GENE INFORMATION
Gene name
VLDLR (HGNC Symbol)
Synonyms
CARMQ1, CHRMQ1, VLDLRCH
Description
Very low density lipoprotein receptor (HGNC Symbol)
Entrez gene summary
The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. This gene encodes a lipoprotein receptor that is a member of the LDLR family and plays important roles in VLDL-triglyceride metabolism and the reelin signaling pathway. Mutations in this gene cause VLDLR-associated cerebellar hypoplasia. Alternative splicing generates multiple transcript variants encoding distinct isoforms for this gene. [provided by RefSeq, Aug 2009]
P98155 [Direct mapping] Very low-density lipoprotein receptor Q5VVF5 [Target identity:100%; Query identity:100%] Very low density lipoprotein receptor; Very low density lipoprotein receptor, isoform CRA_a
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Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)