Expression of SURF2 in cancer - Summary - The Human Protein Atlas

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SURF2

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	SURF2
Gene description	Surfeit 2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in all tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA044340
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA044340

GENE INFORMATION
Gene name	SURF2
Synonyms
Description	Surfeit 2 (HGNC Symbol)
Entrez gene summary	This gene shares a bidirectional promoter with surfeit 1 (SURF1; GeneID: 6834), which is located on the opposite strand. It encodes a conserved protein that is expressed in a variety of tissues. [provided by RefSeq, Jul 2013]
Chromosome	9
Cytoband	q34.2
Chromosome location (bp)	133356552 - 133361169
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000148291 (version 83.38)
Entrez gene	6835
UniProt	Q15527 (UniProt - Evidence at protein level)
neXtProt	NX_Q15527
Antibodypedia	SURF2 antibodies

PROTEIN BROWSER

SURF2-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SURF2-001 ENSP00000361032 ENST00000371964	Q15527 [Direct mapping] Surfeit locus protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005575 [cellular_component] GO:0005634 [nucleus] GO:0005730 [nucleolus] GO:0005886 [plasma membrane] GO:0008150 [biological_process] Show all	256 aa 29.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.