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Most of the cancer tissues displayed weak to moderate nuclear staining with additional cytoplasmic positivity in a few cases. Few cases of malignant melanomas and gliomas were strongly stained. Several cases of lymphomas, renal, liver, lung, endometrial and prostate cancers were negative.
Most malignant tissues displayed weak to moderate cytoplasmic and nucleolar positivity. Occasional cases of malignant melanomas, skin, testicular, liver and colorectal cancers displayed strong immunoreactivity. Several cases of malignant lymphomas, renal cancers along with few cases of cervical and pancreatic cancers were negative.
GENE INFORMATION
Gene name
NACC2 (HGNC Symbol)
Synonyms
BEND9, BTBD14A, BTBD31, MGC23427
Description
NACC family member 2, BEN and BTB (POZ) domain containing (HGNC Symbol)