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MSRB2

GENERAL INFORMATION

Gene name

 MSRB2

Gene description

 Methionine sulfoxide reductase B2

Protein class

 Predicted secreted proteins

Predicted localization

 Secreted

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 General cytoplasmic expression with a granular pattern in several tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Approved based on 1 antibody.
HPA027933
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Heart muscle

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 MSRB2 (HGNC Symbol)

Synonyms

 CBS-1, CBS1, CGI-131, MSRB, PILB

Description

 Methionine sulfoxide reductase B2 (HGNC Symbol)

Entrez gene summary

Chromosome

 10

Cytoband

 p12.2

Chromosome location (bp)

 23095506 - 23122013

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000148450 (version 83.38)

Entrez gene

 22921

UniProt

 Q9Y3D2 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9Y3D2

Antibodypedia

 MSRB2 antibodies

PROTEIN BROWSER
MSRB2-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MSRB2-001
ENSP00000365693
ENST00000376510
Q9Y3D2 [Direct mapping]
Methionine-R-sulfoxide reductase B2, mitochondrial
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Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0003779 [actin binding]
GO:0005739 [mitochondrion]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006979 [response to oxidative stress]
GO:0008270 [zinc ion binding]
GO:0030041 [actin filament polymerization]
GO:0030091 [protein repair]
GO:0033743 [peptide-methionine (R)-S-oxide reductase activity]
GO:0055114 [oxidation-reduction process]
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 182 aa
19.5 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.