Expression of BTBD10 in cancer - Summary - The Human Protein Atlas

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BTBD10

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	BTBD10
Gene description	BTB (POZ) domain containing 10
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Nuclear expression in several different tissue types.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Approved based on 1 antibody. HPA046777
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PROGNOSTIC SUMMARY
Prognostic marker in liver cancer (unfavourable).
Liver cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

Endometrial cancer

STAINING SUMMARY

HPA046777

GENE INFORMATION
Gene name	BTBD10 (HGNC Symbol)
Synonyms	GMRP-1, GMRP1, MGC13007
Description	BTB (POZ) domain containing 10 (HGNC Symbol)
Entrez gene summary
Chromosome	11
Cytoband	p15.3
Chromosome location (bp)	13388001 - 13463297
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000148925 (version 83.38)
Entrez gene	84280
UniProt	Q9BSF8 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BSF8
Antibodypedia	BTBD10 antibodies

PROTEIN BROWSER

BTBD10-001	BTBD10-004	BTBD10-005	BTBD10-008	BTBD10-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
BTBD10-001 ENSP00000278174 ENST00000278174	Q9BSF8 [Direct mapping] BTB/POZ domain-containing protein 10 D3DQW7 [Target identity:100%; Query identity:100%] BTB (POZ) domain containing 10, isoform CRA_a; GMRP1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0042327 [positive regulation of phosphorylation] GO:0044342 [type B pancreatic cell proliferation] GO:1901215 [negative regulation of neuron death] Show all	475 aa 53.8 kDa	No	0
BTBD10-004 ENSP00000435257 ENST00000528120	B7Z503 [Direct mapping] BTB (POZ) domain containing 10, isoform CRA_c; BTB/POZ domain-containing protein 10; cDNA FLJ58599, highly similar to BTB/POZ domain-containing protein 10 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] Show all	427 aa 48.3 kDa	No	0
BTBD10-005 ENSP00000431186 ENST00000530907	Q9BSF8 [Direct mapping] BTB/POZ domain-containing protein 10 Show all	Phobius predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0042327 [positive regulation of phosphorylation] GO:0044342 [type B pancreatic cell proliferation] GO:1901215 [negative regulation of neuron death] Show all	483 aa 54.4 kDa	No	0
BTBD10-008 ENSP00000434579 ENST00000529708	E9PPD8 [Direct mapping] BTB/POZ domain-containing protein 10 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		66 aa 7.5 kDa	No	0
BTBD10-009 ENSP00000431572 ENST00000526841	E9PKM7 [Direct mapping] BTB/POZ domain-containing protein 10 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		64 aa 7.2 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.