Expression of FAM57B in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

FAM57B

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	FAM57B
Gene description	Family with sequence similarity 57, member B
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	5
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enriched (glioma)
HPA (cell line):	Cell line enhanced (SCLC-21H, SH-SY5Y)
HPA (normal tissue):	Group enriched (cerebral cortex, testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA030837
	SHOW MORE

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enriched (glioma)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA030837

GENE INFORMATION
Gene name	FAM57B (HGNC Symbol)
Synonyms	DKFZP434I2117
Description	Family with sequence similarity 57, member B (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	p11.2
Chromosome location (bp)	30024427 - 30052978
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000149926 (version 83.38)
Entrez gene	83723
UniProt	Q71RH2 (UniProt - Evidence at transcript level)
neXtProt	NX_Q71RH2
Antibodypedia	FAM57B antibodies

PROTEIN BROWSER

FAM57B-001	FAM57B-003	FAM57B-004	FAM57B-005	FAM57B-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAM57B-001 ENSP00000456854 ENST00000561666	H3BST4 [Direct mapping] Protein FAM57B Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	146 aa 16.4 kDa	Yes	1
FAM57B-003 ENSP00000369863 ENST00000380495	Q71RH2 [Direct mapping] Protein FAM57B F1T0F5 [Target identity:100%; Query identity:100%] Family with sequence similarity 57, member B, isoform CRA_b; Uncharacterized protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0005794 [Golgi apparatus] GO:0016021 [integral component of membrane] GO:0045599 [negative regulation of fat cell differentiation] GO:0046513 [ceramide biosynthetic process] GO:0050291 [sphingosine N-acyltransferase activity] Show all	274 aa 30.6 kDa	No	5
FAM57B-004 ENSP00000279389 ENST00000279389	Q71RH2 [Direct mapping] Protein FAM57B Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Show all	GO:0000139 [Golgi membrane] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0016021 [integral component of membrane] Show all	224 aa 25.2 kDa	No	5
FAM57B-005 ENSP00000457769 ENST00000564806	H3BUS2 [Direct mapping] Protein FAM57B Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	170 aa 18.7 kDa	No	3
FAM57B-009 ENSP00000458640 ENST00000571269	I3L180 [Direct mapping] Protein FAM57B Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Show all		18 aa 2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.