Expression of FAM173B in cancer - Summary - The Human Protein Atlas

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FAM173B

TISSUE

CELL

PATHOLOGY

GENERAL INFORMATION
Gene name	FAM173B
Gene description	Family with sequence similarity 173, member B
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

ANTIBODY IHC RELIABILITY
Reliability score	Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Prognostic marker in breast cancer (unfavourable).
Breast cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Pending cancer tissue analysis
STAINING SUMMARY

GENE INFORMATION
Gene name	FAM173B
Synonyms
Description	Family with sequence similarity 173, member B (HGNC Symbol)
Entrez gene summary
Chromosome	5
Cytoband	p15.2
Chromosome location (bp)	10226330 - 10249897
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000150756 (version 83.38)
Entrez gene	134145
UniProt	Q6P4H8 (UniProt - Evidence at protein level)
neXtProt	NX_Q6P4H8
Antibodypedia	FAM173B antibodies

PROTEIN BROWSER

FAM173B-001	FAM173B-002	FAM173B-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAM173B-001 ENSP00000422338 ENST00000511437	Q6P4H8 [Direct mapping] Protein FAM173B Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	233 aa 26.1 kDa	No	1
FAM173B-002 ENSP00000420876 ENST00000510047	Q6P4H8 [Direct mapping] Protein FAM173B Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	216 aa 24.2 kDa	No	1
FAM173B-003 ENSP00000280330 ENST00000280330	J3KN90 [Direct mapping] Protein FAM173B; Uncharacterized protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		69 aa 8.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.