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Most malignant cells showed moderate to strong cytoplasmic staining with a granular pattern. A majority of skin and cervical cancers were weakly stained or negative.
Malignancies displayed weak to moderate cytoplasmic positivity in most cases. A few cases of colorectal and thyroid cancers were strongly staining. A majority of skin and renal cancers were negative.
This gene encodes a beta-ketoacyl synthetase. The encoded enzyme is required for elongation of fatty acid chains in the mitochondria. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2009]
Enzymes ENZYME proteins Transferases SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Enzymes ENZYME proteins Transferases SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)