Cell atlas - DIP2C - The Human Protein Atlas

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DIP2C

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Nucleoplasm
	Vesicles

Human cell
	Cytosol
	Nucleoplasm
	Vesicles

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GENERAL INFORMATION
Gene name	DIP2C
Gene description	Disco-interacting protein 2 homolog C
Protein class	Plasma proteins Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the cytosol & nucleoplasm. In addition localized to vesicles.
RNA cell category	Cell line enhanced (U-2197)
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (approved), Cytosol (approved)
Additional location	In addition localized to the Vesicles (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA059325
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (U-2197) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the cytosol & nucleoplasm. In addition localized to vesicles.

Main location

Nucleoplasm (approved), Cytosol (approved)

Additional location

Vesicles (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA059325	BJ	Nucleoplasm
	HPA059325	BJ	Cytosol
	HPA059325	MCF7	Nucleoplasm
	HPA059325	MCF7	Cytosol
	HPA059325	U-2 OS	Nucleoplasm
			Vesicles
			Cytosol

GENE INFORMATION
Gene name	DIP2C (HGNC Symbol)
Synonyms	KIAA0934
Description	Disco-interacting protein 2 homolog C (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the disco-interacting protein homolog 2 family. The protein shares strong similarity with a Drosophila protein which interacts with the transcription factor disco and is expressed in the nervous system. [provided by RefSeq, Oct 2008]
Chromosome	10
Cytoband	p15.3
Chromosome location (bp)	274190 - 689668
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000151240 (version 83.38)
Entrez gene	22982
UniProt	Q9Y2E4 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y2E4
Antibodypedia	DIP2C antibodies

PROTEIN BROWSER

DIP2C-001	DIP2C-003	DIP2C-004	DIP2C-005	DIP2C-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DIP2C-001 ENSP00000280886 ENST00000280886	Q9Y2E4 [Direct mapping] Disco-interacting protein 2 homolog C Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0003824 [catalytic activity] GO:0005575 [cellular_component] GO:0005634 [nucleus] GO:0008134 [transcription factor binding] GO:0008150 [biological_process] GO:0008152 [metabolic process] Show all	1556 aa 170.8 kDa	No	0
DIP2C-003 ENSP00000397571 ENST00000421992	H0Y5A8 [Direct mapping] Disco-interacting protein 2 homolog C Show all	Phobius predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0008152 [metabolic process] GO:0016021 [integral component of membrane] Show all	240 aa 26.1 kDa	No	0
DIP2C-004 ENSP00000414462 ENST00000434695	H0Y7Q3 [Direct mapping] Disco-interacting protein 2 homolog C Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0008152 [metabolic process] Show all	130 aa 14.8 kDa	No	0
DIP2C-005 ENSP00000489203 ENST00000634311		Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0005634 [nucleus] GO:0008134 [transcription factor binding] GO:0008152 [metabolic process] Show all	1622 aa 178.1 kDa	No	4
DIP2C-201 ENSP00000370907 ENST00000381496	E7EPU2 [Direct mapping] Disco-interacting protein 2 homolog C Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0005634 [nucleus] GO:0008134 [transcription factor binding] GO:0008152 [metabolic process] Show all	1537 aa 168.6 kDa	No	4

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.