Cell atlas - VENTX - The Human Protein Atlas

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VENTX

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Nucleoli fibrillar center

Human cell
	Cytosol
	Nucleoli

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GENERAL INFORMATION
Gene name	VENTX
Gene description	VENT homeobox
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleoli (fibrillar center). In addition localized to the cytosol.
RNA cell category	Group enriched (NB-4, NTERA-2)
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoli fibrillar center (uncertain)
Additional location	In addition localized to the Cytosol (uncertain)

DATA RELIABILITY
Reliability score	Uncertain based on 1 antibody. HPA050955
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Group enriched (NB-4, NTERA-2) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleoli (fibrillar center). In addition localized to the cytosol.

Main location

Nucleoli fibrillar center (uncertain)

Additional location

Cytosol (uncertain)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA050955	CACO-2	Nucleoli fibrillar center
	HPA050955	U-2 OS	Nucleoli fibrillar center
	HPA050955	U-2 OS	Cytosol

GENE INFORMATION
Gene name	VENTX (HGNC Symbol)
Synonyms	HPX42B, VENTX2
Description	VENT homeobox (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the Vent family of homeodomain proteins. The encoded protein may function as a transcriptional repressor and be involved in mesodermal patterning and hemopoietic stem cell maintenance. Multiple pseudogenes exist for this gene. A transcribed pseudogene located on chromosome X may lead to antigen production in certain melanomas. [provided by RefSeq, Jul 2008]
Chromosome	10
Cytoband	q26.3
Chromosome location (bp)	133237404 - 133241929
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000151650 (version 83.38)
Entrez gene	27287
UniProt	O95231 (UniProt - Evidence at protein level)
neXtProt	NX_O95231
Antibodypedia	VENTX antibodies

PROTEIN BROWSER

VENTX-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
VENTX-001 ENSP00000357556 ENST00000325980	O95231 [Direct mapping] Homeobox protein VENTX Show all	Predicted intracellular proteins Transcription factors Helix-turn-helix domains Protein evidence (Kim et al 2014) Show all	GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0007275 [multicellular organismal development] GO:0043565 [sequence-specific DNA binding] Show all	258 aa 27.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.