Expression of RNF144A in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

RNF144A

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	RNF144A
Gene description	Ring finger protein 144A
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Cell line enhanced (HMC-1)
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Membranous expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA049939
	SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in stomach cancer (unfavourable), endometrial cancer (unfavourable) and head and neck cancer (favourable).
Stomach cancer p<0.001 Endometrial cancer p<0.001 Head and neck cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA049939

GENE INFORMATION
Gene name	RNF144A (HGNC Symbol)
Synonyms	KIAA0161, RNF144, UBCE7IP4
Description	Ring finger protein 144A (HGNC Symbol)
Entrez gene summary	The protein encoded by this protein contains a RING finger, a motif known to be involved in protein-DNA and protein-protein interactions. The mouse counterpart of this protein has been shown to interact with Ube2l3/UbcM4, which is an ubiquitin-conjugating enzyme involved in embryonic development. [provided by RefSeq, Jul 2008]
Chromosome	2
Cytoband	p25.1
Chromosome location (bp)	6917392 - 7068286
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000151692 (version 83.38)
Entrez gene	9781
UniProt	P50876 (UniProt - Evidence at protein level)
neXtProt	NX_P50876
Antibodypedia	RNF144A antibodies

PROTEIN BROWSER

RNF144A-001	RNF144A-003	RNF144A-005	RNF144A-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RNF144A-001 ENSP00000321330 ENST00000320892	P50876 [Direct mapping] E3 ubiquitin-protein ligase RNF144A Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0000151 [ubiquitin ligase complex] GO:0000209 [protein polyubiquitination] GO:0005515 [protein binding] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0008270 [zinc ion binding] GO:0016021 [integral component of membrane] GO:0016874 [ligase activity] GO:0030659 [cytoplasmic vesicle membrane] GO:0031624 [ubiquitin conjugating enzyme binding] GO:0032436 [positive regulation of proteasomal ubiquitin-dependent protein catabolic process] GO:0042787 [protein ubiquitination involved in ubiquitin-dependent protein catabolic process] GO:0061630 [ubiquitin protein ligase activity] Show all	292 aa 32.9 kDa	No	1
RNF144A-003 ENSP00000414420 ENST00000416587	C9JLH4 [Direct mapping] E3 ubiquitin-protein ligase RNF144A Show all	Predicted intracellular proteins Show all	GO:0004842 [ubiquitin-protein transferase activity] GO:0016567 [protein ubiquitination] Show all	55 aa 6.4 kDa	No	0
RNF144A-005 ENSP00000402645 ENST00000433456	C9JLH4 [Direct mapping] E3 ubiquitin-protein ligase RNF144A Show all	Predicted intracellular proteins Show all	GO:0004842 [ubiquitin-protein transferase activity] GO:0016567 [protein ubiquitination] Show all	55 aa 6.4 kDa	No	0
RNF144A-006 ENSP00000411616 ENST00000432850	H7C3G0 [Direct mapping] E3 ubiquitin-protein ligase RNF144A Show all	Predicted intracellular proteins Show all	GO:0004842 [ubiquitin-protein transferase activity] GO:0005515 [protein binding] GO:0008270 [zinc ion binding] GO:0016567 [protein ubiquitination] Show all	264 aa 29.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.