Expression of CCDC74B in cancer - Summary - The Human Protein Atlas

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CCDC74B

TISSUE

CELL

PATHOLOGY

GENERAL INFORMATION
Gene name	CCDC74B
Gene description	Coiled-coil domain containing 74B
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	7
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enhanced (SCLC-21H, SH-SY5Y)
HPA (normal tissue):	Tissue enhanced (fallopian tube, testis)

Protein evidence

Evidence at transcript level

ANTIBODY IHC RELIABILITY
Reliability score	Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable) and breast cancer (favourable).
Renal cancer p<0.001 Breast cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION
Pending cancer tissue analysis
STAINING SUMMARY

GENE INFORMATION
Gene name	CCDC74B (HGNC Symbol)
Synonyms	DKFZp434E2321
Description	Coiled-coil domain containing 74B (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	q21.1
Chromosome location (bp)	130139287 - 130145134
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000152076 (version 83.38)
Entrez gene	91409
UniProt	Q96LY2 (UniProt - Evidence at transcript level)
neXtProt	NX_Q96LY2
Antibodypedia	CCDC74B antibodies

PROTEIN BROWSER

CCDC74B-001	CCDC74B-005	CCDC74B-007	CCDC74B-010	CCDC74B-011	CCDC74B-012	CCDC74B-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CCDC74B-001 ENSP00000308873 ENST00000310463	Q96LY2 [Direct mapping] Coiled-coil domain-containing protein 74B Show all	Predicted intracellular proteins Show all		380 aa 41.8 kDa	No	0
CCDC74B-005 ENSP00000386294 ENST00000409943	Q96LY2 [Direct mapping] Coiled-coil domain-containing protein 74B Show all	Predicted intracellular proteins Show all		314 aa 35.1 kDa	No	0
CCDC74B-007 ENSP00000386644 ENST00000409128	B8ZZB0 [Direct mapping] Coiled-coil domain-containing protein 74B Show all	Predicted intracellular proteins Show all		204 aa 22.4 kDa	No	0
CCDC74B-010 ENSP00000399683 ENST00000457413	H7C1C8 [Direct mapping] Coiled-coil domain-containing protein 74B Show all	Predicted intracellular proteins Show all		205 aa 22.1 kDa	No	0
CCDC74B-011 ENSP00000386303 ENST00000409234	E9PG54 [Direct mapping] Coiled-coil domain-containing protein 74B Show all	Predicted intracellular proteins Show all		225 aa 24.8 kDa	No	0
CCDC74B-012 ENSP00000396549 ENST00000441670	C9JC78 [Direct mapping] Coiled-coil domain-containing protein 74B Show all	Predicted intracellular proteins Show all		160 aa 17.7 kDa	No	0
CCDC74B-201 ENSP00000376710 ENST00000392984	E7ESC5 [Direct mapping] Coiled-coil domain-containing protein 74B Show all	Predicted intracellular proteins Show all		274 aa 29.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.