Expression of CFC1B in cancer - Summary - The Human Protein Atlas

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CFC1B

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	CFC1B
Gene description	Cripto, FRL-1, cryptic family 1B
Protein class	Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Not detected
HPA (normal tissue):	Not detected

Protein evidence

No evidence

Protein expression
normal tissue

Cytoplasmic and membranous positivity in several tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Caution, targets protein from more than one gene. Secreted protein, tissue location of RNA and protein might differ and correlation is complex.
Reliability score	Uncertain based on 1 antibody. HPA041773
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

Pancreatic cancer

STAINING SUMMARY

HPA041773

GENE INFORMATION
Gene name	CFC1B
Synonyms
Description	Cripto, FRL-1, cryptic family 1B (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	q21.1
Chromosome location (bp)	130521197 - 130528604
Protein evidence	No evidence (all genes)
Ensembl	ENSG00000152093 (version 83.38)
Entrez gene	653275
UniProt	P0CG36 (UniProt - Inferred from homology)
neXtProt	NX_P0CG36
Antibodypedia	CFC1B antibodies

PROTEIN BROWSER

CFC1B-001	CFC1B-201	CFC1B-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CFC1B-001 ENSP00000281882 ENST00000281882	P0CG36 [Direct mapping] Cryptic family protein 1B Show all	SCAMPI predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005515 [protein binding] GO:0005576 [extracellular region] GO:0007369 [gastrulation] Show all	223 aa 24.6 kDa	Yes	0
CFC1B-201 ENSP00000483368 ENST00000619050	A0A087X0G3 [Direct mapping] Cryptic family protein 1B Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all		191 aa 20.4 kDa	Yes	0
CFC1B-202 ENSP00000480160 ENST00000620207	A0A087WWE4 [Direct mapping] Cryptic family protein 1B Show all	SCAMPI predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all		148 aa 16.4 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.