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RPP38

GENERAL INFORMATION

Gene name

 RPP38

Gene description

 Ribonuclease P/MRP 38kDa subunit

Protein class

 Enzymes
Predicted intracellular proteins
Ribosomal proteins

Predicted localization

 Intracellular

Number of transcripts

 6
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Prognostic marker in urothelial cancer (favourable), liver cancer (unfavourable) and renal cancer (unfavourable).
Urothelial cancer p<0.001
Liver cancer p<0.001
Renal cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 RPP38

Synonyms

Description

 Ribonuclease P/MRP 38kDa subunit (HGNC Symbol)

Entrez gene summary

Chromosome

 10

Cytoband

 p13

Chromosome location (bp)

 15097180 - 15139818

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000152464 (version 83.38)

Entrez gene

 10557

UniProt

 P78345 (UniProt - Evidence at protein level)

neXtProt

 NX_P78345

Antibodypedia

 RPP38 antibodies

PROTEIN BROWSER
RPP38-001
RPP38-002
RPP38-003
RPP38-004
RPP38-005
RPP38-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RPP38-001
ENSP00000367439
ENST00000378197
P78345 [Direct mapping]
Ribonuclease P protein subunit p38
Show all
Enzymes
   ENZYME proteins
   Hydrolases
Ribosomal proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004526 [ribonuclease P activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005655 [nucleolar ribonuclease P complex]
GO:0008033 [tRNA processing]
GO:0010467 [gene expression]
GO:0090501 [RNA phosphodiester bond hydrolysis]
GO:0090502 [RNA phosphodiester bond hydrolysis, endonucleolytic]
Show all
 283 aa
31.8 kDa 		No 0
RPP38-002
ENSP00000367444
ENST00000378202
P78345 [Direct mapping]
Ribonuclease P protein subunit p38
Show all
Enzymes
   ENZYME proteins
   Hydrolases
Ribosomal proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004526 [ribonuclease P activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005655 [nucleolar ribonuclease P complex]
GO:0008033 [tRNA processing]
GO:0010467 [gene expression]
GO:0090501 [RNA phosphodiester bond hydrolysis]
GO:0090502 [RNA phosphodiester bond hydrolysis, endonucleolytic]
Show all
 283 aa
31.8 kDa 		No 0
RPP38-003
ENSP00000367445
ENST00000378203
P78345 [Direct mapping]
Ribonuclease P protein subunit p38
Show all
Enzymes
   ENZYME proteins
   Hydrolases
Ribosomal proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004526 [ribonuclease P activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005655 [nucleolar ribonuclease P complex]
GO:0008033 [tRNA processing]
GO:0010467 [gene expression]
GO:0090501 [RNA phosphodiester bond hydrolysis]
GO:0090502 [RNA phosphodiester bond hydrolysis, endonucleolytic]
Show all
 283 aa
31.8 kDa 		No 0
RPP38-004
ENSP00000367443
ENST00000378201
Q5VUC9 [Direct mapping]
Ribonuclease P protein subunit p38
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 145 aa
16.4 kDa 		No 0
RPP38-005
ENSP00000402635
ENST00000441850
Q5VUC3 [Direct mapping]
Ribonuclease P protein subunit p38
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 169 aa
19 kDa 		No 0
RPP38-201
ENSP00000478982
ENST00000616640
P78345 [Direct mapping]
Ribonuclease P protein subunit p38
Show all
Enzymes
   ENZYME proteins
   Hydrolases
Ribosomal proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004526 [ribonuclease P activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005655 [nucleolar ribonuclease P complex]
GO:0008033 [tRNA processing]
GO:0010467 [gene expression]
GO:0090501 [RNA phosphodiester bond hydrolysis]
GO:0090502 [RNA phosphodiester bond hydrolysis, endonucleolytic]
Show all
 283 aa
31.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.