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AHCTF1

GENERAL INFORMATION

Gene name

 AHCTF1

Gene description

 AT hook containing transcription factor 1

Protein class

 Predicted intracellular proteins
Transporters

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Ubiquitous cytoplasmic expression.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Uncertain based on 1 antibody.
HPA031658
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable).
Renal cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA031658

GENE INFORMATION

Gene name

 AHCTF1 (HGNC Symbol)

Synonyms

 ELYS

Description

 AT hook containing transcription factor 1 (HGNC Symbol)

Entrez gene summary

Chromosome

 1

Cytoband

 q44

Chromosome location (bp)

 246839098 - 246931978

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000153207 (version 83.38)

Entrez gene

 25909

UniProt

 Q8WYP5 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8WYP5

Antibodypedia

 AHCTF1 antibodies

PROTEIN BROWSER
AHCTF1-001
AHCTF1-002
AHCTF1-005

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
AHCTF1-001
ENSP00000355464
ENST00000366508
Q8WYP5 [Direct mapping]
Protein ELYS
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Transporters
   Transporter channels and pores
   THUMBUP predicted membrane proteins
   Phobius predicted secreted proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0000278 [mitotic cell cycle]
GO:0000777 [condensed chromosome kinetochore]
GO:0000785 [chromatin]
GO:0000910 [cytokinesis]
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0005643 [nuclear pore]
GO:0005654 [nucleoplasm]
GO:0005829 [cytosol]
GO:0007264 [small GTPase mediated signal transduction]
GO:0015031 [protein transport]
GO:0016363 [nuclear matrix]
GO:0031080 [nuclear pore outer ring]
GO:0031965 [nuclear membrane]
GO:0034399 [nuclear periphery]
GO:0051028 [mRNA transport]
GO:0051292 [nuclear pore complex assembly]
GO:0070062 [extracellular exosome]
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 2301 aa
256 kDa 		No 0
AHCTF1-002
ENSP00000355465
ENST00000326225
Q8WYP5 [Direct mapping]
Protein ELYS
Show all
Transporters
   Transporter channels and pores
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000278 [mitotic cell cycle]
GO:0000777 [condensed chromosome kinetochore]
GO:0000785 [chromatin]
GO:0000910 [cytokinesis]
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005634 [nucleus]
GO:0005643 [nuclear pore]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007264 [small GTPase mediated signal transduction]
GO:0015031 [protein transport]
GO:0016363 [nuclear matrix]
GO:0031080 [nuclear pore outer ring]
GO:0031965 [nuclear membrane]
GO:0034399 [nuclear periphery]
GO:0051028 [mRNA transport]
GO:0051292 [nuclear pore complex assembly]
GO:0070062 [extracellular exosome]
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 2275 aa
253.5 kDa 		No 0
AHCTF1-005
ENSP00000417115
ENST00000478568
C9J5C5 [Direct mapping]
Protein ELYS
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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 67 aa
7.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.