Expression of CCDC148 in cancer - Summary - The Human Protein Atlas

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CCDC148

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	CCDC148
Gene description	Coiled-coil domain containing 148
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enhanced (CAPAN-2, HBF TERT88, SCLC-21H)
HPA (normal tissue):	Tissue enhanced (parathyroid gland, testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification. Antibody staining not consistent with RNA expression data.
Reliability score	Uncertain based on 1 antibody. HPA042626
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PROGNOSTIC SUMMARY
Prognostic marker in thyroid cancer (favourable).
Thyroid cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA042626

GENE INFORMATION
Gene name	CCDC148 (HGNC Symbol)
Synonyms	MGC125588
Description	Coiled-coil domain containing 148 (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	q24.1
Chromosome location (bp)	158171081 - 158456753
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000153237 (version 83.38)
Entrez gene	130940
UniProt	Q8NFR7 (UniProt - Evidence at protein level)
neXtProt	NX_Q8NFR7
Antibodypedia	CCDC148 antibodies

PROTEIN BROWSER

CCDC148-001	CCDC148-004	CCDC148-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CCDC148-001 ENSP00000283233 ENST00000283233	Q8NFR7 [Direct mapping] Coiled-coil domain-containing protein 148 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	591 aa 71.1 kDa	No	0
CCDC148-004 ENSP00000386583 ENST00000409889	Q8NFR7 [Direct mapping] Coiled-coil domain-containing protein 148 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	255 aa 30.4 kDa	No	0
CCDC148-007 ENSP00000386674 ENST00000409187	B8ZZV3 [Direct mapping] Coiled-coil domain-containing protein 148 Show all	Predicted intracellular proteins Show all		600 aa 72.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.